As the number of patients diagnosed with endometrial cancer rises, so does the number of patients who undergo surgical treatment, consisting of radical hysterectomy, bilateral salpingo-oophorectomy, and bilateral pelvic lymphadenectomy or lymph node sampling. The latter entail intra- and post-surgical complications, such as lymphedema and increased intra-operative bleeding, which often outweigh their benefits. Sentinel Lymph Node (SLN) sampling is now common practice in surgical management of breast cancer, as it provides important information about the disease without jeopardizing surgical radicality and patient outcomes. While this technique has also been shown to be feasible in patients with endometrial cancer, there is little consensus on several aspects, such as tracer injection volume and site, pathological ultrastaging, and result interpretation. The aim of this review is to analyze the current literature on SLN assessment in order to help standardize the procedure.
随着子宫内膜癌确诊患者数量的增加，接受手术治疗的患者数量也在上升，手术通常包括根治性子宫切除术、双侧输卵管卵巢切除术以及双侧盆腔淋巴结清扫术或淋巴结取样。后者常伴随术中及术后并发症，如淋巴水肿和术中出血增加，这些并发症往往超过了其带来的益处。前哨淋巴结（SLN）取样目前在乳腺癌的外科治疗中已成为常规操作，因为它能在不影响手术彻底性和患者预后的情况下，提供关于疾病的重要信息。尽管该技术已被证明在子宫内膜癌患者中同样可行，但在示踪剂注射量和部位、病理超分期以及结果解读等多个方面仍缺乏共识。本综述旨在分析当前关于前哨淋巴结评估的文献，以帮助标准化该操作流程。
Sentinel Lymph Node Assessment in Endometrial Cancer: A Review
肿瘤(癌症)患者之家