肿瘤(癌症)患者之家
首页
癌症知识
肿瘤中医药治疗
肿瘤药膳
肿瘤治疗技术
前沿资讯
临床试验招募
登录/注册
VIP特权
广告
广告加载中...

文章:

肿瘤疾病动物疼痛管理:阿片类药物对免疫与肿瘤细胞平衡的影响

Pain Management in Animals with Oncological Disease: Opioids as Influencers of Immune and Tumor Cellular Balance

原文发布日期:29 August 2024

DOI: 10.3390/cancers16173015

类型: Article

开放获取: 是

 

英文摘要:

Advancements in understanding pain physiopathology have historically challenged animals’ absence of pain senses. Studies have demonstrated that animals have comparable neural pain pathways, suggesting that cats and dogs likely experience pain similarly to humans. Understanding brain circuits for effective pain control has been crucial to adjusting pain management to the patient’s individual responses and current condition. The refinement of analgesic strategies is necessary to better cater to the patient’s demands. Cancer pain management searches to ascertain analgesic protocols that enhance patient well-being by minimizing or abolishing pain and reducing its impact on the immune system and cancer cells. Due to their ability to reduce nerve sensitivity, opioids are the mainstay for managing moderate and severe acute pain; however, despite their association with tumor progression, specific opioid agents have immune-protective properties and are considered safe alternatives to analgesia for cancer patients.

 

摘要翻译: 

对疼痛病理生理学认识的进步,历来挑战着动物缺乏痛感的观点。研究表明,动物拥有与人类相似的神经疼痛通路,这表明猫和狗可能以类似于人类的方式感受疼痛。理解有效疼痛控制的大脑回路,对于根据患者的个体反应和当前状况调整疼痛管理至关重要。镇痛策略的精细化改进是更好地满足患者需求的必要途径。癌症疼痛管理致力于确定能够通过减轻或消除疼痛、减少其对免疫系统和癌细胞的影响来提升患者生活质量的镇痛方案。阿片类药物因其降低神经敏感性的能力,成为管理中重度急性疼痛的主要手段;然而,尽管与肿瘤进展相关,特定的阿片类药物具有免疫保护特性,被认为是癌症患者镇痛的安全替代选择。

 

原文链接:

Pain Management in Animals with Oncological Disease: Opioids as Influencers of Immune and Tumor Cellular Balance

广告
广告加载中...