Patients with inflammatory bowel diseases (IBDs), including both ulcerative colitis (UC) and Crohn’s disease (CD), are at a higher risk of developing colorectal cancer (CRC). However, advancements in endoscopic imaging techniques, integrated surveillance programs, and improved medical therapies have led to a decrease in the incidence of CRC among IBD patients. Currently, the management of patients with IBD who have a history of or ongoing active malignancy is an unmet need. This involves balancing the risk of cancer recurrence/progression with the potential exacerbation of IBD if the medications are discontinued. The objective of this review is to provide an updated summary of the epidemiology, causes, risk factors, and surveillance approaches for CRC in individuals with IBD, and to offer practical guidance on managing IBD patients with history of previous or active cancer.
炎症性肠病（IBD）患者，包括溃疡性结肠炎（UC）和克罗恩病（CD），罹患结直肠癌（CRC）的风险较高。然而，随着内镜成像技术的进步、综合监测项目的实施以及药物治疗的改善，IBD患者的CRC发病率已呈下降趋势。目前，对于有恶性肿瘤病史或活动性恶性肿瘤的IBD患者的管理仍存在未满足的临床需求。这需要在癌症复发/进展的风险与停药可能导致IBD病情加重之间取得平衡。本综述旨在更新关于IBD患者CRC的流行病学、病因、危险因素及监测方法的总结，并为有既往或活动性癌症病史的IBD患者的管理提供实用指导。
肿瘤(癌症)患者之家