Immediate breast reconstruction (IBR) following a mastectomy, combined with radiotherapy, presents a multifaceted approach to breast cancer treatment, balancing oncological safety and aesthetic outcomes. IBR, typically involving the use of implants or autologous tissue, aims to restore breast morphology directly after a mastectomy, minimizing the psychological and physical impacts. However, integrating radiotherapy with IBR is complex due to the potential adverse effects on reconstructed tissues. Radiotherapy, essential for reducing local recurrence, can induce fibrosis, capsular contracture, and compromised aesthetic results. This narrative review covers the current trends in the sequencing of breast reconstruction and radiotherapy. We discuss patient selection, timing of radiotherapy, and reconstructive techniques, with special attention paid to quality-of-life outcomes that are increasingly reported in clinical trials. Emerging evidence supports the feasibility of IBR with careful patient selection and tailored therapeutic approaches, although ongoing research is necessary to refine protocols and enhance outcomes. Overall, IBR in the context of radiotherapy remains a promising but intricate treatment modality, requiring a nuanced balance between cancer control and aesthetic restoration.
乳房切除术后即刻乳房重建（IBR）联合放疗是一种多层次的乳腺癌治疗策略，旨在平衡肿瘤学安全性与美学效果。IBR通常采用植入物或自体组织移植，力求在乳房切除术后直接恢复乳房形态，以减轻患者的心理与生理负担。然而，放疗与IBR的结合具有复杂性，因其可能对重建组织产生不良影响。作为降低局部复发率的关键手段，放疗可能导致纤维化、包膜挛缩及美学效果受损。本文综述了当前乳房重建与放疗时序安排的研究进展，重点探讨患者选择、放疗时机及重建技术，并特别关注临床试验中日益重视的生活质量指标。最新证据表明，通过精细的患者筛选和个体化治疗方案，IBR联合放疗具有可行性，但仍需持续研究以优化治疗方案并提升疗效。总体而言，放疗背景下的IBR仍是一种前景广阔但错综复杂的治疗模式，需要在肿瘤控制与美学重建之间实现精准平衡。
肿瘤(癌症)患者之家