文章：

阑尾神经内分泌肿瘤患者淋巴结病变相关的病理特征

Pathological Features Associated with Lymph Node Disease in Patients with Appendiceal Neuroendocrine Tumors

原文发布日期：22 August 2024

DOI: 10.3390/cancers16162922

类型: Article

开放获取: 是

英文摘要：

This study aimed to evaluate the role of pathological features beyond tumor size in the risk of lymph node metastasis in appendiceal neuroendocrine tumors. Analyzing data from the national cancer database, we found that among 5353 cases, 18.8% had lymph node metastasis. Focusing on tumors smaller than 2 cm, a subject of considerable debate in treatment strategies, we identified lymphovascular invasion as one of the strongest predictors of lymph node disease. Interestingly, extension into the subserosa and beyond, a current factor in the staging system, was not a strong predictor. These findings suggest that careful interpretation of pathological features is needed when selecting therapeutic approaches using current staging systems.

摘要翻译： 

本研究旨在评估阑尾神经内分泌肿瘤中，除肿瘤大小外，病理特征对淋巴结转移风险的影响。通过分析国家癌症数据库的数据，我们发现，在5353例病例中，淋巴结转移率为18.8%。针对目前治疗策略中争议较大的小于2厘米的肿瘤，我们发现淋巴血管侵犯是淋巴结转移最强的预测因素之一。值得注意的是，目前分期系统中考虑的因素——肿瘤侵犯浆膜下层及更深层组织——并非强预测因素。这些发现提示，在使用现有分期系统选择治疗方案时，需谨慎解读病理特征。

原文链接：

Pathological Features Associated with Lymph Node Disease in Patients with Appendiceal Neuroendocrine Tumors