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文章:

老年与年轻患者胃癌机器人手术后短期疗效比较:一项回顾性队列研究

Comparison of Short-Term Outcomes after Robotic Surgery for Gastric Cancer in Elderly and Younger Patients: A Retrospective Cohort Study

原文发布日期:15 August 2024

DOI: 10.3390/cancers16162849

类型: Article

开放获取: 是

 

英文摘要:

Robot-assisted surgery has recently been introduced to overcome some drawbacks and technical limitations in performing laparoscopic gastrectomy. The aim of the present study was to evaluate the feasibility and safety of robotic gastrectomy in elderly patients. The study enrolled 143 patients who underwent robotic gastrectomy in a single high-volume centre. All patients were divided into two groups based on age: elderly group ≥ 75 years old (EG; n = 64) and non-elderly group < 75 years old (NEG; n = 79). Comorbidities were significantly more frequent in the EG (95.3%) than in the NEG (81%) (p= 0.011). Similarly, the percentage of ASA 3 patients was significantly higher in the EG than in the NEG (43.8% vs. 24.0%, respectively;p= 0.048). Nevertheless, the incidence of Clavien–Dindo grade III and IV complications did not differ significantly between the two groups (10.9% in the EG and 6.3% in the NEG;p= 0.852). Moreover, operative time, re-operation rate, mean number of harvested lymph nodes, 30-day mortality, and median hospital stay were similar within the two groups. Our study suggests that robotic gastrectomy can be performed safely for elderly patients. In particular, chronological age does not seem to affect either the clinical or oncological short-term outcomes after robotic gastrectomy.

 

摘要翻译: 

为克服腹腔镜胃切除术的某些缺陷与技术限制,机器人辅助手术近年被引入临床应用。本研究旨在评估机器人胃切除术在老年患者中的可行性与安全性。研究纳入143例在单一高手术量中心接受机器人胃切除术的患者,按年龄分为两组:老年组(≥75岁,64例)与非老年组(<75岁,79例)。老年组合并症发生率显著高于非老年组(95.3% vs. 81%,p=0.011),ASA 3级患者比例亦显著更高(43.8% vs. 24.0%,p=0.048)。然而两组间Clavien-Dindo III-IV级并发症发生率无显著差异(老年组10.9% vs. 非老年组6.3%,p=0.852)。此外,两组在手术时间、再手术率、淋巴结清扫数目、30天死亡率及中位住院时间方面均无显著差异。研究表明机器人胃切除术可安全应用于老年患者,特别是实际年龄并不影响机器人胃切除术后的临床与肿瘤学短期结局。

 

原文链接:

Comparison of Short-Term Outcomes after Robotic Surgery for Gastric Cancer in Elderly and Younger Patients: A Retrospective Cohort Study

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