Advancements in cancer treatment and early detection have extended survival rates, transforming many cancers into chronic conditions. However, cancer diagnosis and treatment can trigger significant psychological distress, including depression and anxiety, impacting patient outcomes and care. This study aimed to examine the prevalence of and identify the risk factors for depression and anxiety among cancer patients. A cross-sectional study was conducted, including patients under the care of the oncology department at a tertiary medical center between June 2021 and October 2023. Depression and anxiety were assessed using the Patient-Reported Outcomes Measurement Information System (PROMIS) short forms. Logistic regression analysis identified risk factors for depression and anxiety. The study population included 159 patients, with 40.3% reporting worsening mental health, but only about half of them received therapy. Among the study participants, 22.6% experienced symptoms of depression and 30.2% experienced symptoms of anxiety. Single-cancer patients and those with metastases were at increased risk for depression, while those with a disease duration of more than a year and patients with female-specific cancer were more likely to experience anxiety. Given the high prevalence of mental health deterioration in cancer patients, closer monitoring and validated assessment tools are essential to improve depression and anxiety diagnosis and facilitate early interventions.
随着癌症治疗与早期检测技术的进步，患者生存率显著提升，使许多癌症逐渐转变为慢性疾病。然而，癌症的诊断与治疗过程可能引发显著的心理困扰，包括抑郁和焦虑，进而影响患者的治疗效果与照护质量。本研究旨在探讨癌症患者抑郁与焦虑的患病率及其风险因素。研究采用横断面设计，纳入2021年6月至2023年10月期间在某三级医疗中心肿瘤科接受治疗的患者。使用患者报告结局测量信息系统（PROMIS）简版量表评估抑郁与焦虑症状，并通过逻辑回归分析识别相关风险因素。研究共纳入159例患者，其中40.3%报告心理健康状况恶化，但仅约半数患者接受了心理干预。在参与者中，22.6%存在抑郁症状，30.2%存在焦虑症状。单发癌症患者及转移性癌症患者抑郁风险更高，而病程超过一年及患有女性特异性癌症的患者更易出现焦虑症状。鉴于癌症患者心理健康恶化发生率较高，有必要加强临床监测并采用经过验证的评估工具，以提升抑郁与焦虑的识别率，促进早期干预。
Mental Health Challenges in Cancer Patients: A Cross-Sectional Analysis of Depression and Anxiety
肿瘤(癌症)患者之家