Spinal metastases occur in up to 40% of patients with cancer. Of these cases, 10% become symptomatic. The reported incidence of spinal metastases has increased in recent years due to innovations in imaging modalities and oncological treatments. As the incidence of spinal metastases rises, so does the demand for improved treatments and treatment algorithms, which now emphasize greater multidisciplinary collaboration and are increasingly customized per patient. Uniquely, we discuss the potential clinical applications of AI and NGS in the treatment of spinal metastases. Material and Methods: A PubMed search for articles published from 2000 to 2023 regarding spinal metastases and artificial intelligence in healthcare was completed. After screening for relevance, the key findings from each study were summarized in this update. Results: This review summarizes the evidence from studies reporting on treatment modalities for spinal metastases, including minimally invasive surgery (MIS), external beam radiation therapy (EBRT), stereotactic radiosurgery (SRS), CFR-PEEK instrumentation, radiofrequency ablation (RFA), next-generation sequencing (NGS), artificial intelligence, and predictive models.
高达40%的癌症患者会发生脊柱转移，其中10%会出现临床症状。近年来，随着影像学技术和肿瘤治疗手段的创新，脊柱转移瘤的报道发病率呈上升趋势。随着脊柱转移瘤发病率的增加，对改进治疗方案和治疗流程的需求也日益增长，当前的治疗策略更强调多学科协作，并越来越多地根据患者个体情况进行定制化治疗。本文特别探讨了人工智能和下一代测序技术在脊柱转移瘤治疗中的潜在临床应用。材料与方法：通过PubMed数据库检索2000年至2023年间发表的关于脊柱转移瘤及医疗人工智能的相关文献，经相关性筛选后，将各研究的关键发现汇总于本综述。结果：本综述总结了脊柱转移瘤治疗方式的相关研究证据，包括微创手术、外照射放疗、立体定向放射外科手术、CFR-PEEK内固定器械、射频消融术、下一代测序技术、人工智能及预测模型等。
肿瘤(癌症)患者之家