文章：

按县社会经济状况、组织学类型及种族/族裔划分的子宫癌女性患者五年相对生存率总体分析

Five-Year Relative Survival Rates of Women Diagnosed with Uterine Cancer by County-Level Socioeconomic Status Overall and across Histology and Race/Ethnicity

原文发布日期：1 August 2024

DOI: 10.3390/cancers16152747

类型: Article

开放获取: 是

英文摘要：

Understanding socioeconomic factors contributing to uterine cancer survival disparities is crucial, especially given the increasing incidence of uterine cancer, which disproportionately impacts racial/ethnic groups. We investigated the impact of county-level socioeconomic factors on five-year survival rates of uterine cancer overall and by histology across race/ethnicity. We included 333,013 women aged ≥ 30 years with microscopically confirmed uterine cancers (2000–2018) from the Surveillance, Epidemiology, and End Results 22 database followed through 2019. Age-standardized five-year relative survival rates were compared within race/ethnicity and histology, examining the differences across tertiles of county-level percent (%)

摘要翻译： 

理解导致子宫癌生存差异的社会经济因素至关重要，尤其是在子宫癌发病率不断上升且对种族/族裔群体影响不均的背景下。本研究探讨了县级社会经济因素对不同种族/族裔群体子宫癌总体及组织学分型五年生存率的影响。我们基于监测、流行病学和最终结果（SEER）22数据库，纳入了2000年至2018年间经显微镜确诊的333,013名30岁及以上女性子宫癌患者，随访至2019年。通过比较不同种族/族裔和组织学分型间的年龄标准化五年相对生存率，分析了县级高中以下教育程度比例、贫困率（低于贫困线150%）、失业率、家庭收入中位数及城市化程度三分位数间的差异。总体年龄调整五年相对生存率为77.7%。居住在最弱势县（第三分位）的患者生存率最低，最优势县（第一分位）最高：教育程度（74.7% vs. 80.2%）、贫困率（72.9% vs. 79.8%）、失业率（75.7% vs. 80.5%）及收入（第一分位73.3% vs. 第三分位78.1%）。县级社会经济特征对不同组织学分型生存率的影响较小。研究发现，无论肿瘤特征和社会经济状况如何，非西班牙裔黑人和非西班牙裔美国原住民/阿拉斯加原住民女性均存在显著的生存差异。这些发现进一步揭示了县级社会经济特征如何影响不同种族/族裔群体间的子宫癌生存不平等。

原文链接：

Five-Year Relative Survival Rates of Women Diagnosed with Uterine Cancer by County-Level Socioeconomic Status Overall and across Histology and Race/Ethnicity