The rate of major complications and 30-day mortality after surgery for metastatic spinal tumors is relatively high. While most studies have focused on baseline comorbid conditions and operative parameters as risk factors, there is limited data on the influence of other parameters such as sociodemographic or socioeconomic data on outcomes. We retrospectively analyzed data from 165 patients who underwent surgery for spinal metastases between 2012–2023. The primary outcome was development of major complications (i.e., Clavien–Dindo Grade III–IV complications), and the secondary outcome was 30-day mortality (i.e., Clavien–Dindo Grade V complications). An exploratory data analysis that included sociodemographic, socioeconomic, clinical, oncologic, and operative parameters was performed. Following multivariable analysis, independent predictors of Clavien–Dindo Grade III–IV complications were Frankel Grade A–C, lower modified Bauer score, and lower Prognostic Nutritional Index. Independent predictors of Clavien–Dindo Grade V complications) were lung primary cancer, lower modified Bauer score, lower Prognostic Nutritional Index, and use of internal fixation. No sociodemographic or socioeconomic factor was associated with either outcome. Sociodemographic and socioeconomic factors did not impact short-term surgical outcomes for metastatic spinal tumor patients in this study. Optimization of modifiable factors like nutritional status may be more important in improving outcomes in this complex patient population.
脊柱转移瘤术后主要并发症发生率及30天死亡率相对较高。现有研究多聚焦于基线合并症及手术参数等风险因素，而社会人口学或社会经济参数对预后的影响数据有限。本研究回顾性分析了2012年至2023年间接受脊柱转移瘤手术的165例患者资料。主要结局指标为主要并发症（即Clavien-Dindo III-IV级并发症）发生情况，次要结局指标为30天死亡率（即Clavien-Dindo V级并发症）。研究对社会人口学、社会经济、临床、肿瘤学及手术参数进行了探索性数据分析。多变量分析显示，Clavien-Dindo III-IV级并发症的独立预测因素包括Frankel分级A-C级、改良Bauer评分较低及预后营养指数较低；Clavien-Dindo V级并发症的独立预测因素包括肺癌原发灶、改良Bauer评分较低、预后营养指数较低以及使用内固定术。社会人口学及社会经济因素与两种结局均无显著关联。本研究表明，社会人口学及社会经济因素未对脊柱转移瘤患者的短期手术结局产生影响。对此类复杂患者群体而言，优化营养状况等可干预因素对改善预后可能更为重要。
肿瘤(癌症)患者之家