Brain metastases pose a significant therapeutic challenge in the field of oncology, necessitating treatments that effectively control disease progression while preserving neurological and cognitive functions. Among various interventions, brachytherapy, which involves the direct placement of radioactive sources into or near tumors or into the resected cavity, can play an important role in treatment. Current literature describes brachytherapy’s capacity to deliver targeted, high-dose radiation while minimizing damage to adjacent healthy tissues—a crucial consideration in the choice of treatment modality. Furthermore, advancements in implantation techniques as well as in the development of different isotopes have expanded its efficacy and safety profile. This review delineates the contemporary applications of brachytherapy in managing brain metastases, examining its advantages, constraints, and associated clinical outcomes, and provides a comprehensive understanding of advances in the use of brachytherapy for brain metastasis treatment, with implications for improved patient outcomes and enhanced quality of life.
脑转移瘤在肿瘤治疗领域构成了显著的治疗挑战，需要既能有效控制疾病进展又能保护神经与认知功能的治疗方案。在多种干预手段中，近距离放射治疗通过将放射源直接植入肿瘤内部或邻近区域，或置于切除腔中，在治疗中发挥着重要作用。现有文献表明，近距离放射治疗能够实现靶向高剂量照射，同时最大限度减少对邻近健康组织的损伤——这是选择治疗方式时的关键考量因素。此外，植入技术的进步以及不同同位素的研发进一步提升了该疗法的有效性与安全性。本文系统阐述了近距离放射治疗在脑转移瘤管理中的当代应用，分析了其优势、局限及相关临床结果，全面梳理了该技术在脑转移治疗领域的最新进展，为改善患者预后及提升生活质量提供了重要参考。
肿瘤(癌症)患者之家