文章：

前列腺癌患者雄激素剥夺治疗启动时骨折预防多学科护理路径的制定

Development of a Multidisciplinary Care Pathway for Fracture Prevention in Men with Prostate Cancer at Initiation of Androgen Deprivation Therapy

原文发布日期：26 July 2024

DOI: 10.3390/cancers16152665

类型: Article

开放获取: 是

英文摘要：

Fracture risk is increased in men with prostate cancer (PCa) receiving Androgen Deprivation Therapy (ADT). However, routine assessment of fracture risk is often not systematically applied. We aimed to establish a comprehensive care pathway for fracture prevention in men with PCa starting ADT. Therefore, a multidisciplinary working group designed and implemented a care pathway using the ‘Knowledge to Action’ framework, based on current Dutch guidelines for PCa, osteoporosis and fracture prevention, and an extensive literature review of other guidelines. The pathway was developed according to a five-step clinical approach including case finding, fracture risk assessment based on risk factors, bone mineral density test, vertebral fracture assessment, differential diagnosis, treatment, and annual follow-up. Our fracture prevention care pathway for patients with PCa at the time of ADT initiation was designed to promote a patient-centered, multidisciplinary approach to facilitate the implementation of early fracture prevention measures.

摘要翻译： 

接受雄激素剥夺疗法（ADT）的前列腺癌（PCa）患者骨折风险显著增加，然而骨折风险的常规评估往往未能系统化实施。本研究旨在为启动ADT治疗的前列腺癌患者建立一套完整的骨折预防综合管理路径。为此，多学科工作组基于荷兰现行前列腺癌诊疗指南、骨质疏松防治指南，并通过系统梳理国际相关指南文献，采用“知识转化行动”框架设计并实施了该管理路径。该路径遵循五步临床路径构建：病例筛查、基于风险因素的骨折风险评估、骨密度检测、椎体骨折评估、鉴别诊断、治疗方案制定及年度随访。我们构建的ADT起始期前列腺癌患者骨折预防管理路径，旨在推行以患者为中心的多学科协作模式，促进早期骨折预防措施的有效实施。

原文链接：

Development of a Multidisciplinary Care Pathway for Fracture Prevention in Men with Prostate Cancer at Initiation of Androgen Deprivation Therapy