Extracellular vesicles, or EVs, are membrane-bound nanocompartments produced by tumor cells. EVs carry proteins and nucleic acids from host cells to target cells, where they can transfer lipids, proteomes, and genetic material to change the function of target cells. EVs serve as reservoirs for mobile cellular signals. The collection of EVs using less invasive processes has piqued the interest of many researchers. Exosomes carry substances that can suppress the immune system. If the results of exosome screening are negative, immunotherapy will be beneficial for GC patients. In this study, we provide an update on EVs and GC based on ongoing review papers and clinical trials.
细胞外囊泡（EVs）是由肿瘤细胞产生的膜结合纳米结构。它们携带宿主细胞的蛋白质和核酸至靶细胞，通过传递脂质、蛋白质组及遗传物质改变靶细胞功能，成为可移动细胞信号的载体。采用微创方式收集EVs的技术引起了众多研究者的关注。外泌体携带的特定物质可抑制免疫系统功能，若外泌体筛查结果为阴性，则免疫疗法对胃癌患者具有积极治疗价值。本研究基于最新综述文献与临床试验数据，系统阐述了EVs与胃癌研究的最新进展。
The Importance of Extracellular Vesicle Screening in Gastric Cancer: A 2024 Update
肿瘤(癌症)患者之家