文章：

揭示健康差异：原住民与非原住民澳大利亚人头颈癌趋势比较分析（1998–2015）

Unveiling a Health Disparity: Comparative Analysis of Head and Neck Cancer Trends between First Nations People and Non-Indigenous Australians (1998–2015)

原文发布日期：15 July 2024

DOI: 10.3390/cancers16142548

类型: Article

开放获取: 是

英文摘要：

Background: We aim to assess and compare the HNC trends between the First Nations and non-Indigenous population. Methods: HNC incidence (1998–2013) and mortality (1998–2015) data in First Nations people and non-Indigenous Australians were utilised from the Australian Cancer Database. The age-standardised incidence and mortality trends along with annual percentage changes were analysed using Joinpoint models. Age-standardised incidence and mortality rates according to remoteness, states, and five-year survival rates among First Nations people and non-Indigenous Australians were presented as graphs. Results: First Nations people had over twice the age-standardised incidence (2013; 29.8/100,000 vs. 14.7/100,000) and over 3.5 times the age-standardised mortality rates (2015; 14.2/100,000 vs. 4.1/100,000) than their non-Indigenous counterparts. Both populations saw a decline in mortality, but the decline was only statistically significant in non-Indigenous Australians (17.1% decline, 1998: 4.8/100,000, 2015: 4.1/100,000;p< 0.05). Across all remoteness levels and states, First Nations people consistently had higher age-standardised incidence and mortality rates. Furthermore, the five-year survival rate was lower by 25% in First Nations people. Conclusion: First Nations people continue to shoulder a disproportionate HNC burden compared to non-Indigenous Australians.

摘要翻译： 

背景：本研究旨在评估并比较澳大利亚原住民与非原住民群体头颈部癌症的发病趋势。方法：利用澳大利亚癌症数据库中1998-2013年原住民与非原住民的头颈部癌症发病率数据及1998-2015年死亡率数据，通过Joinpoint模型分析年龄标准化发病率与死亡率趋势及年度变化百分比。研究以图表形式呈现了不同地域分布、各州情况下的年龄标准化发病率与死亡率，以及原住民与非原住民群体的五年生存率差异。结果：2013年原住民年龄标准化发病率（29.8/10万）是非原住民（14.7/10万）的两倍以上；2015年原住民年龄标准化死亡率（14.2/10万）达到非原住民（4.1/10万）的3.5倍以上。虽然两群体死亡率均呈下降趋势，但仅非原住民群体的下降具有统计学显著性（1998年4.8/10万降至2015年4.1/10万，降幅17.1%，p<0.05）。在所有地域层级及各州数据中，原住民的年龄标准化发病率与死亡率均持续高于非原住民。此外，原住民五年生存率较非原住民低25%。结论：与非原住民群体相比，澳大利亚原住民仍承受着不成比例的头颈部癌症疾病负担。

原文链接：

Unveiling a Health Disparity: Comparative Analysis of Head and Neck Cancer Trends between First Nations People and Non-Indigenous Australians (1998–2015)