Cervical cancer continues to have a significant incidence, despite global efforts in HPV vaccination campaigns. Managing this condition involves a diverse team of healthcare professionals. Research in this field is undergoing a period of great revolution in multiple areas, and international guidelines will soon have to adapt to new scientific evidence. This could be true mainly in locally advanced stages, and it could also be true for minimal invasive surgery. This paper aims to summarize and compare the most recent recommendations published by international gynecological oncological societies for patients with cervical cancer. From their comparison, common aspects and disagreements emerged, especially in the diagnostic pathway and follow-up strategies. Several issues that remain to be debated in the literature were addressed and compared, highlighting similarities and differences, from the role of the sentinel lymph node in early stages to that of the adjuvant hysterectomy in locally advanced tumors. On the surgical side, for this last subset of patients, currently, a laparotomic approach is recommended. At the same time, the advent of immunotherapy has just opened up new and promising scenarios in systemic treatment for locally advanced cervical cancer, and international guidelines will soon introduce it into their algorithms.
尽管全球范围内已大力推行HPV疫苗接种运动，宫颈癌的发病率依然居高不下。该疾病的治疗需要多学科医疗团队的协作。当前，宫颈癌研究在多个领域正经历重大变革，国际诊疗指南也即将根据新的科学证据进行调整。这一趋势在局部晚期宫颈癌的治疗中尤为明显，微创手术领域同样面临革新。本文旨在总结并比较国际妇科肿瘤学会针对宫颈癌患者发布的最新诊疗建议。通过对比发现，各指南在诊断路径和随访策略方面存在共识与分歧。研究对现有文献中尚存争议的若干问题进行了探讨与比较，从早期宫颈癌前哨淋巴结的作用到局部晚期肿瘤辅助性子宫切除术的应用，系统梳理了不同观点的异同。在手术方面，针对局部晚期患者，目前仍推荐开腹手术路径。与此同时，免疫疗法的出现为局部晚期宫颈癌的系统治疗开启了崭新前景，预计国际指南将很快将其纳入治疗规范体系。
肿瘤(癌症)患者之家