Background: Primary cutaneous lymphoma (PCL) is a rare form of extranodal non-Hodgkin’s lymphoma characterized by malignant lymphocytes confined to the skin. Accurate diagnosis and staging are crucial for optimal management, yet radiological literature on imaging PCL remains limited. This study aims to delineate the imaging characteristics of PCLs using high and ultra-high frequency ultrasound (UHFUS) and proposes a classification system based on ultrasound findings. Methods: A cohort of 88 individuals with suspected PCL underwent high-resolution ultrasound (HRUS) and color Doppler examination of lesions. Lesions were categorized based on sonographic appearance, and subsequent histopathological assessment confirmed the diagnosis. Results: Ultrasound imaging revealed distinct patterns for primary cutaneous T-cell lymphomas (PCTCL) and primary cutaneous B-cell lymphomas (PCBCL), with characteristic features such as hypoechoic nodules, pseudonodular lesions, and dermal infiltration. Histopathological analysis confirmed the ultrasound findings, supporting the proposed classification system. Conclusions: Ultrasonography, particularly UHFUS, offers valuable insights into the imaging characteristics of primary cutaneous lymphomas, aiding the accurate diagnosis and assessment of treatment response. The proposed classification system based on ultrasound findings enhances the diagnostic approach to PCLs, and paves the way for improved patient care and management strategies.
背景：原发性皮肤淋巴瘤（PCL）是一种罕见的结外非霍奇金淋巴瘤，其特征为恶性淋巴细胞局限于皮肤。准确的诊断与分期对优化治疗至关重要，然而关于PCL影像学的放射学文献仍较为有限。本研究旨在利用高频及超高频超声（UHFUS）描述PCL的影像学特征，并提出基于超声表现的分类系统。 方法：对88例疑似PCL患者进行病灶的高分辨率超声（HRUS）及彩色多普勒检查。根据超声影像特征对病灶进行分类，并通过后续组织病理学评估确认诊断。 结果：超声影像显示原发性皮肤T细胞淋巴瘤（PCTCL）与原发性皮肤B细胞淋巴瘤（PCBCL）具有不同的模式，其特征包括低回声结节、假结节性病变及真皮层浸润等。组织病理学分析证实了超声发现，支持所提出的分类系统。 结论：超声检查，特别是超高频超声，为原发性皮肤淋巴瘤的影像学特征提供了重要依据，有助于准确诊断及评估治疗反应。基于超声表现提出的分类系统优化了PCL的诊断路径，为改善患者护理和治疗策略奠定了基础。
肿瘤(癌症)患者之家