Background: Validated questionnaires of self-reported LEL are important in the assessment and diagnosis of LEL. The aim of this study was to validate and translate a Dutch version of the screening questionnaire, the LELSQ developed and validated by Yost et al. Methods: We tested the questionnaire on a group of healthy women and a group of patients diagnosed with LEL. The translation was carried out using the forward and backward method from English to Dutch. Statistical analyses: SPSS (IBM corp, Armonk, New York, NY, USA) version 28.0.1.0 (001) was used for statistical analysis in the process of validation. The internal consistency was assessed by determining Cronbach’s alpha. The reliability was tested by test–retest reliability. The validity was determined by ROC analysis, and content and face validity were evaluated. Results: The internal consistency score in both groups had a strong value (0.83 to 0.90). The test–retest reliability was also strong in both groups. Face and content validity showed the LELSQ is an easy, understandable questionnaire that is not too time-consuming in the early detection of LEL. The ROC analysis showed an AUC value of 0.93, indicating strong validity. Conclusions: The validated Dutch translation showed high values for internal consistency, test–retest reliability, and validity, which allows us to implement the questionnaire in the early detection of LEL after gynecological cancer treatment.
背景：经过验证的下肢淋巴水肿（LEL）自评问卷对于LEL的评估和诊断至关重要。本研究旨在对Yost等人开发并验证的筛查问卷LELSQ进行荷兰语版本的翻译与验证。方法：我们在健康女性组和确诊LEL的患者组中对该问卷进行了测试。翻译采用英译荷正向与回译法完成。统计分析：验证过程中使用SPSS（IBM公司，美国纽约州阿蒙克市）28.0.1.0(001)版本进行统计分析。通过计算克朗巴赫系数评估内部一致性，采用重测信度检验可靠性，并通过ROC分析及内容效度与表面效度评估确定效度。结果：两组内部一致性系数均呈现强相关性（0.83至0.90）。重测信度在两组中也表现强劲。表面效度与内容效度显示LELSQ问卷简便易懂，在LEL早期筛查中耗时适宜。ROC分析显示曲线下面积（AUC）值为0.93，表明该问卷具有强效度。结论：经验证的荷兰语译本在内部一致性、重测信度及效度方面均表现出优异指标，证明该问卷可应用于妇科癌症治疗后LEL的早期筛查。
肿瘤(癌症)患者之家