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文章:

外阴癌影像学检查

Imaging in Vulval Cancer

原文发布日期:19 June 2024

DOI: 10.3390/cancers16122269

类型: Article

开放获取: 是

 

英文摘要:

Vulval cancer is a rare gynaecological cancer, accounting for 3% of all gynaecological malignancies, with 47,000 cases in 2022 globally. Various imaging modalities are widely used in conjunction with clinical assessment in the diagnosis and staging of vulval cancers; however, there is significant heterogeneity in which modalities are recommended in international guidelines, reflecting the paucity of evidence in this area. We reviewed the current evidence for the role of imaging in vulval cancer. A systematic search of the literature was performed on the PubMed database using the MeSH terms ‘vulval neoplasm’ and ‘diagnostic imaging’. We found that there is insufficient evidence to support the routine use of imaging for primary vulval tumours. For nodal assessment, there is no ideal imaging modality with sensitivity or specificity that is superior to other modalities. For distant metastases, CT CAP and FDG-PET/CT have the most evidence to support their use. In conclusion, the evidence for role of imaging in vulval cancer is limited by the heterogeneity of the study design and diagnostic criteria used in each study and the small sample size and retrospective nature of most studies.

 

摘要翻译: 

外阴癌是一种罕见的妇科恶性肿瘤,占所有妇科恶性肿瘤的3%,2022年全球新增病例约47,000例。在临床评估基础上,多种影像学检查方法被广泛应用于外阴癌的诊断与分期;然而,国际指南中推荐的影像学检查方案存在显著差异,这反映出该领域证据的匮乏。本文系统回顾了影像学在外阴癌诊疗中作用的现有证据。通过使用医学主题词“外阴肿瘤”和“诊断影像学”在PubMed数据库进行系统性文献检索,我们发现目前缺乏足够证据支持影像学检查作为原发性外阴肿瘤的常规诊断手段。在淋巴结评估方面,尚无某种影像学检查方法的敏感性或特异性显著优于其他方法。对于远处转移评估,CT胸部腹部盆腔联合扫描及FDG-PET/CT具有相对充分的证据支持。综上所述,现有研究在设计方案、诊断标准方面存在异质性,且多数研究样本量较小、属于回顾性研究,这些因素共同限制了影像学在外阴癌诊疗中作用的证据质量。

 

原文链接:

Imaging in Vulval Cancer

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