Cancer is associated with increased muscle weakness, reduced physical functioning, increased fatigue, but also sleep disturbances, including insomnia, that affect quality of life (QoL). Physical activity demonstrated benefits on functional capacity, resilience and cancer-related fatigue, but there is a paucity of available data regarding its effects on insomnia in patients with cancer. This systematic review aims to examine the efficacy of exercise levels with insomnia in cancer patients. A systematic search was performed for articles published in PubMed and Cochrane Library databases from December 2013 to February 2023. Included studies explored insomnia during or after cancer treatment, with various exercise interventions. The search identified nine studies included in this review. Due to substantial heterogeneity in the interventions across studies, meta-analysis was not performed. Three studies reported positive results for insomnia reduction by self-reported outcomes under a supervised aerobic exercise program alone or combined with strength training. The present systematic review establishes the role of exercise interventions for reducing cancer-related insomnia. Further studies are indeed warranted to improve the level of evidence for exercise interventions for implementation in the care of cancer-related insomnia.
癌症常伴随肌肉无力加剧、身体功能下降、疲劳感增强以及包括失眠在内的睡眠障碍，这些症状严重影响患者的生活质量。已有研究表明，体育活动对改善功能状态、增强机体适应能力及缓解癌因性疲乏具有积极作用，但关于其对癌症患者失眠影响的研究数据仍较为匮乏。本系统综述旨在探讨不同运动强度对癌症患者失眠症状的干预效果。研究系统检索了2013年12月至2023年2月期间发表于PubMed和Cochrane Library数据库的相关文献，纳入标准为探讨癌症治疗期间或治疗后失眠问题、并采用各类运动干预措施的研究。最终共纳入9项符合标准的研究。由于各研究干预方案存在显著异质性，未进行荟萃分析。其中三项研究显示，在监督指导下进行有氧运动（单独或联合力量训练）能通过自我报告结果显著改善失眠症状。本系统综述证实了运动干预对缓解癌症相关失眠的积极作用，但未来仍需开展更多研究以提升证据等级，为临床实践中运动干预癌症相关失眠提供更充分的依据。
Exercise Intervention on Insomnia in Patients with a Cancer: A Systematic Review of the Literature
肿瘤(癌症)患者之家