We aimed to report sexual and reproductive outcomes following post-chemotherapy robot-assisted retroperitoneal unilateral lymph node dissection (PC-rRPLND) for non-seminomatous germ cell tumors (NSGCTs) at a high-volume cancer center. We collected records regarding sexual and reproductive outcomes of patients undergoing unilateral PC-rRPLND for stage II NSGCTs from January 2018 to November 2021. Preoperative and postoperative (at 12 months) ejaculatory function as well as erectile function, based on the International Index of Erectile Function-5 (IIEF-5) and Erection Hardness Score (EHS), were assessed. Only patients with a pre-operative IIEF-5 of ≥22 and EHS of ≥3 were included in this analysis. Overall, 22 patients undergoing unilateral PC-rRPLND met the inclusion criteria. Of these, seven (31.8%) patients presented an andrological disorder of any type after PC-rRPLND. Specifically, retrograde ejaculation was present in three (13.6%) patients and hypospermia was present in one (4.5%) patient. Moreover, three (13.6%) patients yielded erectile dysfunction (IIEF-5 < 22 and/or EHS < 3). Lastly, two (9.1%) succeeded in naturally conceiving a child after PC-rRPLND. Retrograde ejaculation is confirmed to be one of the most common complications of PC-rRPLND. Moreover, a non-negligible number of patients experience erectile dysfunction.
本研究旨在报告一家高容量癌症中心对非精原细胞瘤性生殖细胞肿瘤(NSGCTs)患者实施化疗后机器人辅助腹膜后单侧淋巴结清扫术(PC-rRPLND)后的性与生殖结局。我们收集了2018年1月至2021年11月期间因II期NSGCTs接受单侧PC-rRPLND患者的性与生殖结局记录。基于国际勃起功能指数-5(IIEF-5)和勃起硬度评分(EHS),评估了术前及术后(12个月时)的射精功能与勃起功能。本分析仅纳入术前IIEF-5评分≥22且EHS评分≥3的患者。总体而言,22例接受单侧PC-rRPLND的患者符合纳入标准。其中7例(31.8%)患者在PC-rRPLND后出现任何类型的男科功能障碍。具体而言,3例(13.6%)患者出现逆行射精,1例(4.5%)患者出现精液量减少。此外,3例(13.6%)患者出现勃起功能障碍(IIEF-5<22和/或EHS<3)。最后,2例(9.1%)患者在PC-rRPLND后成功自然受孕。逆行射精被证实是PC-rRPLND最常见的并发症之一。此外,相当数量的患者经历了勃起功能障碍。