(1) Background: Currently, an increasing number of women postpone pregnancy beyond the age of 35. Gynecological cancers affect a significant proportion of women of reproductive age, necessitating the development of fertility preservation methods to fulfill family planning. Consequently, providing treatment options that preserve fertility in women diagnosed with gynecological cancers has become a crucial component of care for survivors. (2) Methods: We conducted an extensive search of relevant scientific publications in PubMed and Embase databases and performed a narrative review, including high-quality peer-reviewed research on fertility after being treated for gynecologic cancers, reporting pregnancy rates, birth rates, and pregnancy outcomes in cancer survivors as well as therapeutic options which partially preserve fertility and methods for obtaining a pregnancy in survivors. (3) Discussion: The medicine practiced today is focused on both treating the neoplasm and preserving the quality of life of the patients, with fertility preservation being an important element of this quality. This leads to an improved quality of life, allowing these women to become mothers even in the seemingly adverse circumstances posed by such a pathology. However, although there are guidelines on female fertility preservation in the context of neoplasms, an analysis shows that physicians do not routinely consider it and do not discuss these options with their patients. (4) Conclusions: Advancements in medicine have led to a better understanding and management of gynecological neoplasms, resulting in increased survival rates. Once the battle against these neoplasms is won, the issue of preserving the quality of life for these women arises, with fertility preservation being an important aspect for women who have not yet fulfilled their family planning desires at the time of diagnosis. It is important for patients to be informed about the available options for fertility preservation and to be encouraged to make informed decisions in collaboration with their medical team. Standardized recommendations for onco-fertility into guidelines should be taken into consideration in the future.
（1）背景：当前，越来越多的女性将妊娠计划推迟至35岁以后。妇科肿瘤影响着相当大比例的育龄期女性，因此需要发展生育力保存技术以满足其生育规划需求。为确诊妇科肿瘤的女性提供保留生育功能的治疗方案，已成为肿瘤幸存者综合照护的重要组成部分。（2）方法：我们系统检索了PubMed和Embase数据库中的相关科学文献，通过叙述性综述方法，整合了关于妇科肿瘤治疗后生育功能的高质量同行评议研究，包括肿瘤幸存者的妊娠率、活产率及妊娠结局数据，以及部分保留生育功能的治疗方案和幸存者实现妊娠的技术路径。（3）讨论：现代医学实践在治疗肿瘤的同时，日益重视患者生活质量的维护，而生育力保存正是生活质量的重要维度。这使得女性即使在罹患肿瘤的不利情况下，仍能通过适当干预实现母亲角色。然而，尽管现有肿瘤患者生育力保存指南，分析显示临床医生尚未将其纳入常规诊疗流程，也未能系统化地与患者讨论相关选择。（4）结论：医学进步促进了对妇科肿瘤认知水平和治疗水平的提升，显著提高了患者生存率。在战胜肿瘤后，如何保障这些女性的生活质量成为新的焦点，对于确诊时尚未完成生育规划的女性而言，生育力保存尤为关键。应确保患者充分知晓现有的生育力保存方案，并鼓励其与医疗团队共同制定科学决策。未来有必要将肿瘤生育学的标准化建议纳入临床实践指南。
Navigating Fertility Preservation Options in Gynecological Cancers: A Comprehensive Review
肿瘤(癌症)患者之家