Prostate cancer lung metastasis represents a clinical conundrum due to its implications for advanced disease progression and the complexities it introduces in treatment planning. As the disease progresses to distant sites such as the lung, the clinical management becomes increasingly intricate, requiring tailored therapeutic strategies to address the unique characteristics of metastatic lesions. This review seeks to synthesize the current state of knowledge surrounding prostate cancer metastasis to the lung, shedding light on the diverse array of clinical presentations encountered, ranging from subtle radiological findings to overt symptomatic manifestations. By examining the diagnostic modalities utilized in identifying this metastasis, including advanced imaging techniques and histopathological analyses, this review aims to provide insights into the diagnostic landscape and the challenges associated with accurately characterizing lung metastatic lesions in prostate cancer patients. Moreover, this review delves into the nuances of therapeutic interventions employed in managing prostate cancer lung metastasis, encompassing systemic treatments such as hormonal therapies and chemotherapy, as well as metastasis-directed therapies including surgery and radiotherapy.
前列腺癌肺转移因其对疾病晚期进展的影响及治疗规划复杂性的增加，构成了临床诊疗中的一大难题。当疾病进展至肺等远处部位时，临床管理变得尤为复杂，需要针对转移病灶的独特性质制定个体化治疗策略。本综述旨在整合当前关于前列腺癌肺转移的认知现状，阐明其多样化的临床表现——从细微的影像学发现到明显的症状表现。通过探讨用于识别此类转移的诊断方法，包括先进影像学技术和组织病理学分析，本文旨在深入解析诊断现状及在前列腺癌患者中准确表征肺转移病灶所面临的挑战。此外，本综述还深入探讨了治疗前列腺癌肺转移的干预策略细节，涵盖激素治疗和化疗等系统性治疗，以及包括手术和放疗在内的转移灶定向治疗。
Prostate Cancer Lung Metastasis: Clinical Insights and Therapeutic Strategies
肿瘤(癌症)患者之家