Malignant pleural mesothelioma (MPM) represents a significant health burden, with limited treatment options and poor prognosis. Despite advances in pharmacological and surgical interventions, the role of rehabilitation in MPM management remains underexplored. This study aims to assess the feasibility of a tailored pulmonary rehabilitation intervention addressing physical and respiratory function in MPM patients. A prospective pilot study was conducted on surgically treated MPM patients referred to a cardiopulmonary rehabilitation service. The intervention comprised multidisciplinary educational sessions, physical rehabilitation, and respiratory physiotherapy. Feasibility was evaluated based on dropout rates, adherence to the rehabilitation program, safety, and patient-reported outcomes. Twelve patients were initially enrolled, with seven completing the study. High adherence to physical (T1: 93.43%, T2: 82.56%) and respiratory (T1: 96.2%, T2: 92.5%) rehabilitation was observed, with minimal adverse events reported. Patient satisfaction remained high throughout the study (GPE scores at T1: 1.83 ± 1.17; T2: 2.0 ± 1.15), with improvements noted in physical function, pain management, and health-related quality of life. However, some issues, such as time constraints and lack of continuous supervision, were reported by participants. This pilot study demonstrates the feasibility and potential benefits of a tailored pulmonary rehabilitation intervention in MPM patients. Despite its promising outcomes, further research with larger samples is warranted to validate its efficacy and integrate rehabilitation as a component into the multidisciplinary management of MPM.
恶性胸膜间皮瘤（MPM）是一种具有显著健康负担的疾病，其治疗选择有限且预后不良。尽管药物和手术干预手段有所进展，但康复治疗在MPM管理中的作用仍未得到充分探索。本研究旨在评估针对MPM患者身体及呼吸功能制定的个体化肺康复干预措施的可行性。研究对转诊至心肺康复服务的接受手术治疗的MPM患者开展了一项前瞻性试点研究。干预措施包括多学科教育课程、身体康复训练及呼吸物理治疗。可行性评估基于脱落率、康复计划依从性、安全性及患者报告结局。研究初期纳入12例患者，其中7例完成研究。观察到患者对身体康复（T1：93.43%，T2：82.56%）和呼吸康复（T1：96.2%，T2：92.5%）的依从性较高，不良事件报告极少。研究期间患者满意度持续保持高位（T1时GPE评分：1.83±1.17；T2时：2.0±1.15），并在身体功能、疼痛管理和健康相关生活质量方面观察到改善。然而，参与者报告了时间限制和缺乏持续监督等问题。本试点研究表明，针对MPM患者的个体化肺康复干预具有可行性及潜在获益。尽管结果令人鼓舞，仍需开展更大样本量的进一步研究以验证其疗效，并将康复治疗整合为MPM多学科管理的组成部分。
肿瘤(癌症)患者之家