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文章:

系统综述——磁共振成像在宫颈癌分期中的作用

Systematic Review—Role of MRI in Cervical Cancer Staging

原文发布日期:23 May 2024

DOI: 10.3390/cancers16111983

类型: Article

开放获取: 是

 

英文摘要:

A systematic review of the diagnostic accuracy of MRI in the staging of cervical cancer was conducted based on the literature from the last 5 years. A literature search was performed in the Cochrane Library, EMBASE, MEDLINE and PubMed databases using the MeSH terms “cervical cancer”, “MRI” and “neoplasm staging”. A total of 110 studies were identified, of which 8 fit the inclusion criteria. MRI showed adequate accuracy (74–95%) and high sensitivity (92–100%) in assessing stromal invasion. The data for MRI in terms of assessing vaginal and pelvic side wall involvement were wide ranging and inconclusive. In assessing lymph node metastasis, MRI showed an adequate accuracy (73–90%), specificity (75–91%) and NPV (71–96%) but poor sensitivity (52–75%) and PPV (52–75%). MRI showed high accuracy (95%), sensitivity (78–96%), specificity (87–94%), and NPV (98–100%) but poor PPV (27–42%) in detecting bladder involvement. There was a paucity of data on the use of MRI in assessing rectal involvement in cervical cancer. Overall, the literature was heterogenous in the definitions and language used, which reduced the comparability between articles. More research is required into the diagnostic accuracy of MRI in the staging of cervical cancer and there must be increased consistency in the definitions and language used in the literature.

 

摘要翻译: 

基于近五年文献,对磁共振成像在宫颈癌分期中的诊断准确性进行了系统综述。通过Cochrane图书馆、EMBASE、MEDLINE和PubMed数据库,使用医学主题词"宫颈癌"、"磁共振成像"和"肿瘤分期"进行文献检索。共检索到110项研究,其中8项符合纳入标准。在评估间质浸润方面,磁共振成像显示出足够的准确性(74-95%)和高敏感性(92-100%)。关于阴道及盆腔侧壁侵犯的评估数据范围广泛且无明确结论。在评估淋巴结转移方面,磁共振成像显示出足够的准确性(73-90%)、特异性(75-91%)和阴性预测值(71-96%),但敏感性(52-75%)和阳性预测值(52-75%)较差。在检测膀胱侵犯方面,磁共振成像显示出高准确性(95%)、敏感性(78-96%)、特异性(87-94%)和阴性预测值(98-100%),但阳性预测值较差(27-42%)。关于磁共振成像评估宫颈癌直肠侵犯的数据较为缺乏。总体而言,文献中使用的定义和术语存在异质性,降低了文章间的可比性。需要进一步研究磁共振成像在宫颈癌分期中的诊断准确性,并提高文献中定义和术语使用的一致性。

 

原文链接:

Systematic Review—Role of MRI in Cervical Cancer Staging

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