Background: Liver venous deprivation (LVD) is a recent radiological technique that has shown promising results on Future Remnant Liver (FRL) hypertrophy. The aim of this retrospective study is to compare the segmentary hypertrophy of the FRL after LVD and after portal vein embolization (PVE).Methods: Patients undergoing PVE or LVD between April 2015 and April 2020 were included. The segmentary volumes (seg 4, seg2+3 and seg1) were assessed before and after the radiological procedure.Results: Forty-four patients were included: 26 undergoing PVE, 10 LVD and 8 eLVD. Volume gain of both segment 1 and segments 2+3 was significantly higher after LVD and eLVD than after PVE (segment 1: 27.33 ± 35.37 after PVE vs. 38.73% ± 13.47 after LVD and 79.13% ± 41.23 after eLVD,p= 0.0080; segments 2+3: 40.73% ± 40.53 after PVE vs. 45.02% ± 21.53 after LVD and 85.49% ± 45.51 after eLVD,p= 0.0137), while this was not true for segment 4. FRL hypertrophy was confirmed to be higher after LVD and eLVD than after PVE (33.53% ± 21.22 vs. 68.63% ± 42.03 vs. 28.11% ± 28.33, respectively,p= 0.0280).Conclusions: LVD and eLVD may induce greater hypertrophy of segment 1 and segments 2+3 when compared to PVE.
背景：肝静脉阻断术是一种新兴的放射学技术，其在促进未来残余肝增生方面已展现出良好前景。本研究旨在通过回顾性分析，比较肝静脉阻断术与门静脉栓塞术后未来残余肝各肝段的增生差异。 方法：纳入2015年4月至2020年4月期间接受门静脉栓塞或肝静脉阻断术治疗的患者。通过影像学检查评估介入治疗前后各肝段（第4段、第2+3段及第1段）的体积变化。 结果：共纳入44例患者，其中26例接受门静脉栓塞术，10例接受肝静脉阻断术，8例接受增强型肝静脉阻断术。数据显示，肝静脉阻断术与增强型肝静脉阻断术后第1段及第2+3段的体积增长显著高于门静脉栓塞术（第1段：门静脉栓塞术27.33%±35.37，肝静脉阻断术38.73%±13.47，增强型肝静脉阻断术79.13%±41.23，p=0.0080；第2+3段：门静脉栓塞术40.73%±40.53，肝静脉阻断术45.02%±21.53，增强型肝静脉阻断术85.49%±45.51，p=0.0137），而第4段体积增长在三组间无显著差异。未来残余肝总体积增长在肝静脉阻断术与增强型肝静脉阻断术后显著高于门静脉栓塞术（分别为33.53%±21.22、68.63%±42.03及28.11%±28.33，p=0.0280）。 结论：与门静脉栓塞术相比，肝静脉阻断术及增强型肝静脉阻断术可能更有效地促进第1段及第2+3段肝组织的增生。
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