Numerous studies have been performed onHelicobacter pyloriinfection because of the high death rate linked to this illness and gastric cancer. An update on the key developments in recent years in the investigation ofHelicobacter pyloriand gastric cancer is the goal of this review. Using the search term “Helicobacter pylori, gastric cancer”, the PubMed database was searched. Only papers published in 2024 fulfilled the inclusion criteria. Because case report papers were not part of our investigation, they satisfied the exclusion criteria. Most of the research on the variable genes ofHelicobacter pyloriis guided by genetics to determine potential treatments. Studies on clinical treatments for the eradication ofH. pyloriwith promising therapeutic options are needed. We found the fewest studies related to the immunopathology ofH. pyloriinfection, which is still unknown. In conclusion, priority should be given to this kind of research.
鉴于幽门螺杆菌感染及其相关胃癌的高死亡率，已有大量研究聚焦于此。本综述旨在总结近年来幽门螺杆菌与胃癌研究领域的关键进展。通过检索PubMed数据库，以“幽门螺杆菌、胃癌”为关键词，仅纳入2024年发表的符合收录标准的文献。病例报告类文献因不在本研究范围内，故被排除。目前多数研究基于遗传学指导，探索幽门螺杆菌变异基因以确定潜在治疗方案。针对幽门螺杆菌根除的临床治疗研究仍需进一步开展，以发掘具有前景的治疗策略。我们发现，关于幽门螺杆菌感染的免疫病理学研究数量最少，其机制尚不明确。因此，此类研究应被列为优先方向。
Helicobacter pyloriInfection in Patients with Gastric Cancer: A 2024 Update
肿瘤(癌症)患者之家