Spinal schwannomas are the second most common primary intradural spinal tumor. This study aimed to assess health-related quality of life (HRQoL) and the frequency of return to work after the surgical treatment of spinal schwannomas. HRQoL was compared to a sample of the general population. Patients operated for spinal schwannomas between 2006 and 2020 were identified in a previous study and those alive at follow-up (171 of 180) were asked to participate. Ninety-four (56%) responded and were included in this study. Data were compared to the Stockholm Public Health Survey 2006, a cross-sectional survey of a representative sample of the general population. An analysis for any potential non-response bias was performed and showed no significant differences between the groups. HRQoL was equal between the spinal schwannoma sample and the general population sample in all but one dimension; men in the spinal schwannoma sample reported more moderate problems in the usual activities dimension than men in the general population (p= 0.020). In the schwannoma sample, there were no significant differences between men and women in either of the dimensions EQ-5Dindexor EQVAS. Before surgery, a total of 71 (76%) were working full-time and after surgery almost all (94%) returned to work, most of them within 3 months of surgery. Eighty-nine (95%) of the patients responded that they would accept the surgery for their spinal schwannoma if asked again today. To conclude, surgical treatment of spinal schwannomas is associated with good HRQoL and with a high frequency of return to work.
脊髓神经鞘瘤是第二常见的原发性硬膜内脊髓肿瘤。本研究旨在评估脊髓神经鞘瘤手术治疗后的健康相关生活质量及重返工作岗位的频率，并将健康相关生活质量与普通人群样本进行比较。研究对象来源于前期研究中2006年至2020年间接受手术治疗的脊髓神经鞘瘤患者，对随访存活的180例患者中的171例进行邀请，最终94例（56%）参与本研究。研究数据与2006年斯德哥尔摩公共卫生调查（一项具有代表性的普通人群横断面调查）进行对比。对潜在无应答偏倚的分析显示组间无显著差异。除一个维度外，脊髓神经鞘瘤样本与普通人群样本的健康相关生活质量无差异：神经鞘瘤组男性在常规活动维度报告中度问题的比例显著高于普通男性人群（p=0.020）。在神经鞘瘤样本中，EQ-5D指数与EQ视觉模拟量表各维度均未发现显著的性别差异。术前共有71例（76%）患者从事全职工作，术后近全部患者（94%）重返工作岗位，其中多数在术后3个月内复工。89例（95%）患者表示若重新选择仍会接受手术治疗。综上所述，脊髓神经鞘瘤手术治疗能获得良好的健康相关生活质量，并具有较高的复工率。
肿瘤(癌症)患者之家