The number of children, adolescents and young adults diagnosed with cancer has been rising recently. Various oncological treatments have a detrimental effect on female fertility, and childbearing becomes a major issue during surveillance after recovery. This review discusses the impact of oncological treatments on the ovarian reserve with a thorough explanation of oncologic treatments’ effects and modes of oncofertility procedures. The aim of this review is to help clinicians in making an informed decision about post-treatment fertility in their patients. Ultimately, it may lead to improved overall long-term outcomes among young populations suffering from cancer.
近年来,被诊断患有癌症的儿童、青少年及年轻成人数量呈上升趋势。多种肿瘤治疗方案对女性生育能力存在不良影响,生育问题成为康复后随访阶段的核心议题。本文综述探讨了肿瘤治疗对卵巢储备功能的影响,系统阐释了肿瘤治疗的作用机制及生育力保存技术的实施方式。本综述旨在为临床医生提供决策依据,以协助患者制定治疗后的生育规划。最终,这一举措有望提升年轻癌症患者的长期整体预后。