Breast cancer is amongst the most common invasive cancers in adults. There are established relationships between anti-cancer treatments for breast cancer and cardiovascular side effects. In recent years, novel anti-cancer treatments have been established, as well as the availability of multi-modal cardiac imaging and the sophistication of treatment for cardiac disease. This review provides an in-depth overview regarding the interface of breast cancer and cancer therapy-related cardiovascular toxicity. Specifically, it reviews the pathophysiology of breast cancer, the method of action in therapy-related cardiovascular toxicity from anti-cancer treatment, the use of echocardiography, cardiac CT, MRI, or nuclear medicine as diagnostics, and the current evidence-based treatments available. It is intended to be an all-encompassing review for clinicians caring for patients in this situation.
乳腺癌是成人中最常见的侵袭性癌症之一。乳腺癌抗癌治疗与心血管副作用之间存在明确关联。近年来,新型抗癌疗法不断涌现,同时多模态心脏影像技术的应用日益普及,心脏病治疗手段也日趋精进。本综述深入探讨了乳腺癌与癌症治疗相关心血管毒性之间的交叉领域,具体涵盖乳腺癌的病理生理机制、抗癌治疗引发心血管毒性的作用途径、超声心动图、心脏CT、MRI及核医学等诊断技术的临床应用,以及当前基于循证医学的治疗方案。本文旨在为临床医生提供全面系统的诊疗参考,以更好地服务于此类患者群体。