Glioblastoma is the most common primary malignant brain tumor. While preliminary data point to the positive effects of rehabilitation for patients with glioblastoma, there are unique challenges for clinicians working with this population, including limited life expectancy and/or rapid neurological deterioration. The aim of this article is to review the literature on rehabilitation of adults with glioblastoma, including the feasibility of interventions, their effectiveness, as well as the current clinical practice. The reviewed literature suggests that rehabilitation has been found beneficial for improving the functional prognosis and quality of life of adults with glioblastoma and is desired by patients. We summarize the qualitative evidence regarding healthcare professionals’ and patients’ perspectives on the use of supportive care services. We conclude there is a need for the design of effective rehabilitation programs for patients with glioblastoma, as well as for the development of glioblastoma-specific clinical guidelines for rehabilitation practitioners.
胶质母细胞瘤是最常见的原发性恶性脑肿瘤。尽管初步数据显示康复治疗对胶质母细胞瘤患者具有积极效果,但临床工作者在治疗此类患者时面临独特挑战,包括有限预期寿命和/或快速神经功能恶化。本文旨在综述成人胶质母细胞瘤康复治疗相关文献,涵盖干预措施的可行性、有效性及当前临床实践。文献分析表明,康复治疗有助于改善成人胶质母细胞瘤患者的功能预后与生活质量,且受到患者普遍期待。我们系统总结了医疗专业人员与患者对支持性照护服务认知的质性研究证据。结论指出,亟需为胶质母细胞瘤患者设计有效的康复治疗方案,并制定针对该疾病的康复临床实践指南。
Rehabilitation in People Living with Glioblastoma: A Narrative Review of the Literature