文章：

早发性胃肠道恶性肿瘤：对日益增长的健康隐患的调查

Early-Onset Gastrointestinal Malignancies: An Investigation into a Rising Concern

原文发布日期：18 April 2024

DOI: 10.3390/cancers16081553

类型: Article

开放获取: 是

英文摘要：

There is growing recognition of early-onset gastrointestinal (GI) malignancies in young adults < 50 years of age. While much of the literature has emphasized colorectal cancer, these also include esophageal, gastric, liver, pancreatic, and biliary tract malignancies. Various factors, including lifestyle, hereditary, and environmental elements, have been proposed to explain the rising incidence of GI malignancies in the younger population. This review aims to provide an overview of the recent literature, including global trends and information regarding genetic and environmental risk factors.

摘要翻译： 

近年来，年轻人群（年龄<50岁）中早发性胃肠道恶性肿瘤日益受到关注。现有文献多聚焦于结直肠癌，但该范畴亦涵盖食管癌、胃癌、肝癌、胰腺癌及胆道恶性肿瘤。为解释年轻群体胃肠道恶性肿瘤发病率上升的现象，学界提出了包括生活方式、遗传因素及环境要素在内的多种影响因素。本文旨在梳理近期相关文献，系统阐述全球流行趋势，并综合分析遗传与环境风险因素的相关信息。

原文链接：

Early-Onset Gastrointestinal Malignancies: An Investigation into a Rising Concern