In this review, we discuss the potential role of cannabis and cannabinoids in the management of cancer-related symptoms. There is limited evidence demonstrating the effectiveness of cannabis-based products in treating cancer-related pain and gastrointestinal symptoms such as nausea, vomiting, and loss of appetite. Regarding the role of cannabis-based products in the treatment of insomnia and mood disorders, most studies looked at these symptoms as secondary outcomes with mixed results. Cannabis-based products have adverse effects, ranging from neuropsychiatric to systemic effects to potential drug interactions.
本综述探讨了大麻及大麻素类药物在癌症相关症状管理中的潜在作用。现有证据表明,大麻类产品在缓解癌性疼痛及恶心、呕吐、食欲减退等胃肠道症状方面效果有限。关于大麻类产品对失眠及情绪障碍的治疗作用,多数研究将其作为次要观察指标,结果呈现不一致性。大麻类产品存在从神经精神系统到全身系统的多种不良反应,并可能引发药物相互作用。
Review of the Use of Medicinal Cannabis Products in Palliative Care