Cancer during pregnancy is defined as a tumor diagnosed in a pregnant woman or up to 1-year post-partum. While being a rare disease, cervical cancer is probably one of the most challenging medical conditions, with the dual stake of treating the cancer without compromising its chances for cure, while preserving the pregnancy and the health of the fetus and child. To date, guidelines for gynecological cancers are provided through international consensus meetings with expert panels, giving insights on both diagnosis, treatment, and obstetrical care. However, these expert guidelines do not discuss the various approaches than can be found within the literature, such as alternative staging modalities or innovative surgical approaches. Also, the obstetrical care of women diagnosed with cervical cancer during pregnancy requires specific considerations that are not provided within our current standard of care. This systematic review aims to fill the gap on current issues with regards to the management of cervical cancer during pregnancy and provide future directions within this evolving landscape.
妊娠期癌症定义为在孕妇或产后一年内诊断出的肿瘤。尽管宫颈癌属于罕见疾病,但可能是最具挑战性的医疗状况之一,其双重目标在于:在不影响治愈机会的前提下治疗癌症,同时保护妊娠及胎儿与儿童的健康。迄今为止,妇科癌症的诊疗指南主要通过国际专家共识会议制定,为诊断、治疗及产科护理提供指导。然而,这些专家指南未涵盖文献中可能存在的多种方法,例如替代分期模式或创新手术方式。此外,对妊娠期确诊宫颈癌女性的产科护理需要特殊考量,而当前标准诊疗规范尚未提供相关指导。本系统综述旨在填补当前妊娠期宫颈癌管理中的知识空白,并为这一不断发展的领域提供未来研究方向。
Cervical Cancer Associated with Pregnancy: Current Challenges and Future Strategies