Treatment of penile cancer (PC) focuses on organ preservation, employing various surgical and non-surgical approaches. These interventions may lead to disfigurement, impacting patients’ functional outcomes and psychosocial well-being. We reviewed studies related to penile health and PC up to February 2024, limited to studies published in English. Studies employing health-related quality of life (HRQoL) assessments have identified a detrimental association between aggressive treatment and overall health status, physical functioning, and relationships. In contrast, organ-sparing demonstrates improved measures related to HRQoL and sexual function. Assessment through validated questionnaires reveals diverse voiding outcomes, and varying impacts on QoL and sexual activity, emphasizing the necessity for multidisciplinary personalized care. Studies highlight substantial variations in sexual function, with patients reporting adaptations, reduced satisfaction, and concerns about body image and sexual well-being. Furthermore, unmet needs include challenges in patient–clinician communication, obtaining information, and accessing psychosocial support. Patient experiences underscore the importance of timely diagnosis, treatment access, and addressing psychological consequences. Organ-sparing approaches have higher QoL preservation and sexual function. Individualized support, including sexual therapy, support groups, and family counseling, is essential for post-treatment rehabilitation. Timely diagnosis and comprehensive care are paramount in addressing the multifaceted impact of PC on patients and families.
阴茎癌的治疗侧重于器官保留，采用多种手术与非手术方法。这些干预措施可能导致外形改变，影响患者的功能恢复及心理社会健康。我们回顾了截至2024年2月与阴茎健康及阴茎癌相关的研究，仅限于英文发表文献。采用健康相关生活质量评估的研究发现，激进治疗与整体健康状况、躯体功能及人际关系存在负面关联。相比之下，器官保留策略在健康相关生活质量和性功能方面显示出改善效果。通过标准化问卷评估发现排尿功能结局存在差异，对生活质量和性活动的影响亦不相同，这凸显了多学科个体化治疗的必要性。研究显示性功能存在显著差异，患者普遍报告需要适应过程、满意度降低，并对身体形象和性健康存在担忧。此外，未满足的需求包括医患沟通障碍、信息获取困难以及心理社会支持途径缺乏。患者经历强调了及时诊断、治疗可及性及心理问题处理的重要性。器官保留方法在生活质量维持和性功能保护方面更具优势。个体化支持（包括性治疗、支持小组和家庭咨询）对治疗后康复至关重要。及时诊断和综合护理对于应对阴茎癌对患者及其家庭的多方面影响具有决定性意义。
Improving Quality of Life and Psychosocial Health for Penile Cancer Survivors: A Narrative Review
肿瘤(癌症)患者之家