A large majority of primary hepatobiliary tumors are hepatocellular carcinomas (HCC), with the remainer being cholangiocarcinoma. While surgical resection remains the gold standard treatment for hepatobiliary tumors, relatively few patients are operative candidates, and systemic treatments have limited effectiveness. Locoregional therapies offer significant promise in the management of HCC. Ablation and radioembolization may offer similar outcomes to surgery for early-stage hepatocellular carcinoma while radioembolization and chemoembolization are valuable in the management of advanced disease. There is significantly less evidence for the role of locoregional therapy in the treatment of cholangiocarcinoma, although it appears to be well tolerated.
绝大多数原发性肝胆肿瘤为肝细胞癌，其余为胆管癌。尽管手术切除仍是肝胆肿瘤治疗的金标准，但适合手术的患者相对较少，且全身治疗效果有限。局部区域治疗在肝细胞癌管理中展现出显著潜力。对于早期肝细胞癌，消融治疗和放射性栓塞术可获得与手术相似的疗效；而对于晚期疾病，放射性栓塞术和化疗栓塞术具有重要治疗价值。尽管局部区域治疗在胆管癌治疗中的耐受性良好，但目前支持其疗效的证据明显不足。
Locoregional Therapies for Hepatobiliary Tumors: Contemporary Strategies and Novel Applications
肿瘤(癌症)患者之家