Eccrine porocarcinoma, sharing many features with other skin tumours, is diagnostically challenging. A conventional biopsy might be misleading and surgical excision becomes a primary diagnostic tool and a treatment method. However, the data on surgical safety margins are not consistent. We present a systematic review analysing the surgical margins of porocarcinoma in the head and neck area, which was conducted across the PubMed, Cochrane, and Web of Science databases including studies published from inception to November of 2023. In this systematic review, the PRISMA-ScR checklist was used, and a Cohen’s Kappa coefficient of 0.92 was applied, indicating very good agreement between reviewers. Out of 529 identified articles, 18 studies yielding 20 cases in total were selected for a thorough analysis. Nine (45%) cases were observed in the facial regions, eight (40%) on the scalp, and three (5%) on the neck. The primary treatment of choice was wide local excision with safety margins ranging from 3 to 22 mm (mean: 10.1). It demonstrated that surgical margins do not differ by age or anatomic regions, with the main point of reference being the tumour size. As observed, the bigger the tumour, the wider the safety margins were. However, the limited disclosure of surgical safety margins in analysed case reports impeded our ability to define the minimum safety margins. Further investigation and a consensus on recommended safety margins are required.
小汗腺汗孔癌因与其他皮肤肿瘤具有诸多相似特征，在诊断上颇具挑战性。传统活检可能产生误导，手术切除因此成为主要诊断手段和治疗方法。然而，关于手术安全切缘的数据尚不一致。本研究通过系统综述分析了头颈部汗孔癌的手术切缘范围，检索范围涵盖PubMed、Cochrane和Web of Science数据库，收录自建库至2023年11月发表的研究。本系统综述采用PRISMA-ScR清单，评审者间一致性检验显示科恩卡帕系数为0.92，表明评审者间具有高度一致性。在529篇初筛文献中，最终纳入18项研究共20个病例进行深入分析。其中9例（45%）位于面部区域，8例（40%）位于头皮，3例（5%）位于颈部。主要治疗方案为扩大局部切除术，安全切缘范围在3至22毫米之间（均值：10.1毫米）。研究表明手术切缘范围不受年龄或解剖区域影响，主要参考依据为肿瘤大小。观察发现肿瘤越大，所需安全切缘越宽。然而，现有病例报告对手术安全切缘的披露有限，阻碍了我们确定最小安全切缘的能力。未来需要进一步研究并就推荐安全切缘达成共识。
肿瘤(癌症)患者之家