文章：

低风险早期乳腺癌保乳术后采用间质多导管近距离放射治疗进行加速部分乳腺照射的十年结果

Ten-Year Results of Accelerated Partial-Breast Irradiation with Interstitial Multicatheter Brachytherapy after Breast-Conserving Surgery for Low-Risk Early Breast Cancer

原文发布日期：13 March 2024

DOI: 10.3390/cancers16061138

类型: Article

开放获取: 是

英文摘要：

Patients with an early carcinoma of the breast are commonly treated by breast-conserving surgery (BCS) and postoperative radiotherapy. Partial-breast irradiation has gained acceptance in the last few years. Between December 2008 and December 2017, 182 low-risk breast cancer patients treated by BCS in the four university hospitals of the province of Las Palmas and treated with APBI using interstitial multicatheter brachytherapy were included in this study. After a mean follow-up for survivors of 10 years, the treatment was shown to be safe, as no severe acute/late toxicity (grade ≥ 3) was observed. The 10-year IBTR was 1.7% (95%CI: 0.7–2.7%), and the cause-specific survival was 94.9% (95%CI: 93.2–96.6%). We suggest that multicatheter brachytherapy after BCS is safe and effective in early breast cancer patients.

摘要翻译： 

早期乳腺癌患者通常采用保乳手术联合术后放疗的治疗方案。近年来，部分乳腺照射技术逐渐获得临床认可。本研究纳入2008年12月至2017年12月期间，在拉斯帕尔马斯省四所大学医院接受保乳手术的低危乳腺癌患者182例，所有患者均采用组织间插植多导管近距离放疗进行加速部分乳腺照射。经过平均10年的随访观察（针对存活患者），该治疗方案显示出良好的安全性，未发现≥3级的急性/晚期毒性反应。10年同侧乳腺肿瘤复发率为1.7%（95%CI：0.7–2.7%），疾病特异性生存率达94.9%（95%CI：93.2–96.6%）。研究结果表明，保乳术后采用多导管近距离放疗对早期乳腺癌患者安全有效。

原文链接：

Ten-Year Results of Accelerated Partial-Breast Irradiation with Interstitial Multicatheter Brachytherapy after Breast-Conserving Surgery for Low-Risk Early Breast Cancer