文章：

卵巢恶性布伦纳瘤：文献系统综述

Malignant Brenner Tumor of the Ovary: A Systematic Review of the Literature

原文发布日期：9 March 2024

DOI: 10.3390/cancers16061106

类型: Article

开放获取: 是

英文摘要：

Background: Malignant Brenner tumors are rare ovarian tumors, accounting for less than 1% of malignant ovarian neoplasms. The aim of this manuscript is to systematically review the current literature concerning malignant Brenner tumors. Methods: We searched three medical databases (PubMed, Scopus, and Web of Science) for relevant articles published until 15 September 2023. Results: After applying inclusion and exclusion criteria, 48 manuscripts describing 115 cases were included in this study from the English literature. Conclusions: We analyzed the demographic, clinical, pathological, and oncological characteristics of 115 patients with malignant Brenner tumors. The statistical analysis showed that recurrence was marginally statistically significantly related to tumor stage and was more common in patients with ascites and in women with abnormal CA-125 levels; patients that were treated with lymphadenectomy had better disease-specific survival.

摘要翻译： 

背景：恶性勃勒纳瘤是一种罕见的卵巢肿瘤，占恶性卵巢肿瘤的比例不足1%。本文旨在系统回顾当前关于恶性勃勒纳瘤的文献。方法：我们检索了截至2023年9月15日发表的三个医学数据库（PubMed、Scopus和Web of Science）中的相关文章。结果：在应用纳入和排除标准后，本研究从英文文献中纳入了48篇描述115例病例的手稿。结论：我们分析了115例恶性勃勒纳瘤患者的人口统计学、临床、病理学和肿瘤学特征。统计分析显示，复发与肿瘤分期在统计学上呈边缘显著相关，且在腹水患者和CA-125水平异常的女性中更为常见；接受淋巴结清扫术治疗的患者具有更好的疾病特异性生存率。

原文链接：

Malignant Brenner Tumor of the Ovary: A Systematic Review of the Literature