Craniopharyngioma (CP) treatment, including surgery and radiotherapy, can have short- and long-term vascular side effects. Hypothalamic damage is related to morbid obesity and may increase the lifelong risk of experiencing vascular events in CP patients. This review summarized the available evidence regarding vascular complications in adamantinomatous or papillary CP patients, whatever their age at diagnosis. Three databases (Medline, CINAHL, Web of Science) were searched (06/2023) to retrieve eligible articles. The search was limited to peer-reviewed articles. Titles, abstracts, and full texts were screened by two independent reviewers, and data were extracted using a self-developed grid. Seventy-two studies were included in this review; the majority were case reports. Reported vascular sequela that occurred due to surgery were fusiform dilation of the carotid artery, stroke, vasospasm, hemorrhage, and aneurysm. Related conditions that emerged due to radiotherapy included Moyamoya syndrome and cavernoma. Cardiovascular morbidity and mortality often lead to hypothalamic obesity and metabolic syndrome in CP patients. Vascular damage is a rare complication of CP treatment. Surgical strategies should protect the surrounding hypothalamic and vascular structures. Patients receiving radiotherapy, particularly at a young age, should undergo magnetic resonance angiography monitoring to identify possible neurovascular sequela during post-treatment care.
颅咽管瘤（CP）的治疗，包括手术和放疗，可能引发短期和长期的血管副作用。下丘脑损伤与病态肥胖相关，并可能增加CP患者终生发生血管事件的风险。本综述总结了关于成釉细胞型或乳头型CP患者血管并发症的现有证据，不论其诊断时的年龄。检索了三个数据库（Medline、CINAHL、Web of Science）（截至2023年6月）以获取符合条件的文献，检索范围限定于同行评审文章。由两名独立评审员筛选标题、摘要和全文，并使用自行设计的表格提取数据。本综述共纳入72项研究，其中大部分为病例报告。报道中因手术引起的血管后遗症包括颈动脉梭形扩张、卒中、血管痉挛、出血和动脉瘤。因放疗引起的相关病症包括烟雾病和海绵状血管瘤。心血管疾病发病率和死亡率常导致CP患者出现下丘脑性肥胖和代谢综合征。血管损伤是CP治疗中一种罕见的并发症。手术策略应保护周围的下丘脑和血管结构。接受放疗的患者，尤其是年幼患者，应在治疗后护理期间接受磁共振血管造影监测，以识别可能的神经血管后遗症。
Vascular Morbidity and Mortality in Craniopharyngioma Patients—A Scoping Review
肿瘤(癌症)患者之家