Patient-reported outcome (PRO) scores have been utilized more frequently, but the relationship of PRO scores to determinants of health and social inequities has not been widely studied. Our goal was to determine the association of PRO scores with social determinants. All patients with a new cancer diagnosis who completed a PRO survey from 2020 to 2022 were included. The PRO survey recorded scores for depression, fatigue, pain interference and physical function. Higher depression, fatigue and pain scores indicated more distress. Higher physical condition scores indicated improved functionality. A total of 1090 patients were included. Married patients had significantly better individual PRO scores for each domain. Patients who were able to use the online portal to complete their survey also had better individual scores. Male patients and non-White patients had worse pain scores than female and White patients, respectively. Patients with prostate cancer had the best scores while patients with head and neck and lung cancer had the worst scores. PRO scores varied by cancer disease site and stage. Social support may act in combination with specific patient/tumor factors to influence PRO scores. These findings present opportunities to address patient support at institutional levels.
患者报告结局评分的使用日益频繁，但其与健康决定因素及社会不平等性之间的关联尚未得到广泛研究。本研究旨在探讨患者报告结局评分与社会决定因素的相关性。研究纳入2020年至2022年间所有新确诊癌症并完成患者报告结局调查的患者。该调查记录了抑郁、疲劳、疼痛干扰及躯体功能四个维度的评分，其中抑郁、疲劳和疼痛评分越高表明痛苦程度越高，而躯体功能评分越高则代表功能状态越好。 研究共纳入1090例患者。已婚患者在各项评分中均显著优于未婚患者。能够使用在线平台完成调查的患者其个体评分也更为理想。男性患者与非白人患者的疼痛评分分别较女性患者和白人患者更差。前列腺癌患者的综合评分最佳，而头颈癌与肺癌患者的评分最差。患者报告结局评分随癌症原发部位及分期呈现显著差异。社会支持可能与特定患者/肿瘤因素共同影响患者报告结局评分。这些发现为在机构层面完善患者支持体系提供了改进方向。
Association of Social Determinants with Patient-Reported Outcomes in Patients with Cancer
肿瘤(癌症)患者之家