文章：

看似脊髓肿瘤实非肿瘤

It Looks Like a Spinal Cord Tumor but It Is Not

原文发布日期：29 February 2024

DOI: 10.3390/cancers16051004

类型: Article

开放获取: 是

英文摘要：

Differentiating neoplastic from non-neoplastic spinal cord pathologies may be challenging due to overlapping clinical and radiological features. Spinal cord tumors, which comprise only 2–4% of central nervous system tumors, are rarer than non-tumoral myelopathies of inflammatory, vascular, or infectious origins. The risk of neurological deterioration and the high rate of false negatives or misdiagnoses associated with spinal cord biopsies require a cautious approach. Facing a spinal cord lesion, prioritizing more common non-surgical myelopathies in differential diagnoses is essential. A comprehensive radiological diagnostic approach is mandatory to identify spinal cord tumor mimics. The diagnostic process involves a multi-step approach: detecting lesions primarily using MRI techniques, precise localization of lesions, assessing lesion signal intensity characteristics, and searching for potentially associated anomalies at spinal cord and cerebral MRI. This review aims to delineate the radiological diagnostic approach for spinal cord lesions that may mimic tumors and briefly highlight the primary pathologies behind these lesions.

摘要翻译： 

区分脊髓肿瘤性与非肿瘤性病变可能具有挑战性，因为其临床表现和影像学特征常存在重叠。脊髓肿瘤仅占中枢神经系统肿瘤的2-4%，相较于炎症性、血管性或感染性等非肿瘤性脊髓病变更为罕见。由于脊髓活检存在神经功能恶化的风险，且假阴性或误诊率较高，因此需要采取审慎的诊疗策略。面对脊髓病变时，鉴别诊断中优先考虑更常见的非手术性脊髓病变至关重要。必须采用全面的影像学诊断方法来识别脊髓肿瘤的类似病变。诊断过程包含多步骤方法：主要通过MRI技术检测病变、精确定位病灶、评估病灶信号强度特征，并在脊髓及脑部MRI中寻找可能相关的异常表现。本综述旨在阐述可能模拟肿瘤的脊髓病变的影像学诊断路径，并简要概述这些病变背后的主要病理类型。

原文链接：

It Looks Like a Spinal Cord Tumor but It Is Not