文章：

结直肠癌肝转移的当代外科治疗策略

Contemporary Surgical Management of Colorectal Liver Metastases

原文发布日期：26 February 2024

DOI: 10.3390/cancers16050941

类型: Article

开放获取: 是

英文摘要：

Colorectal cancer is the third most common cancer in the United States and the second most common cause of cancer-related death. Approximately 20–30% of patients will develop hepatic metastasis in the form of synchronous or metachronous disease. The treatment of colorectal liver metastasis (CRLM) has evolved into a multidisciplinary approach, with chemotherapy and a variety of locoregional treatments, such as ablation and portal vein embolization, playing a crucial role. However, resection remains a core tenet of management, serving as the gold standard for a curative-intent therapy. As such, the input of a dedicated hepatobiliary surgeon is paramount for appropriate patient selection and choice of surgical approach, as significant advances in the field have made management decisions extremely nuanced and complex. We herein aim to review the contemporary surgical management of colorectal liver metastasis with respect to both perioperative and operative considerations.

摘要翻译： 

结直肠癌是美国第三大常见癌症，也是癌症相关死亡的第二大主要原因。约20%-30%的患者会发生同时性或异时性肝转移。结直肠癌肝转移的治疗已发展为多学科综合模式，其中化疗及消融、门静脉栓塞等多种局部治疗手段发挥着关键作用。然而，手术切除仍是治疗的核心原则，作为根治性治疗的金标准。因此，肝胆专科医生的参与对患者选择和手术方式决策至关重要，该领域的重大进展使得治疗决策变得极其精细复杂。本文旨在从围手术期和手术操作两个维度，系统评述结直肠癌肝转移的现代外科治疗策略。

原文链接：

Contemporary Surgical Management of Colorectal Liver Metastases