There is a rising trend in the consumption of dietary supplements, especially among adults, with the purpose of improving health. While marketing campaigns tout the potential health benefits of using dietary supplements, it is critical to evaluate the potential harmful effects associated with these supplements as well. The majority of the scarce research on the potential harmful effects of vitamins focuses on the acute or chronic toxicities associated with the use of dietary supplements. Quality research is still required to further investigate the risks of long-term use of dietary supplements, especially the risk of developing cancers. The present review concentrates on studies that have investigated the association between the risk of developing cancers and associated mortality with the risk of dietary supplements. Such an association has been reported for several vitamins, minerals, and other dietary supplements. Even though several of these studies come with their own shortcomings and critics, they must draw attention to further investigate long-term adverse effects of dietary supplements and advise consumers and healthcare providers to ponder the extensive use of dietary supplements.
膳食补充剂的消费呈上升趋势，尤其在成年人群体中，其目的在于改善健康状况。尽管营销活动宣传使用膳食补充剂可能带来的健康益处，但评估这些补充剂可能产生的有害影响同样至关重要。目前关于维生素潜在有害影响的研究大多集中在膳食补充剂使用相关的急性或慢性毒性上。仍需高质量研究进一步探讨长期使用膳食补充剂的风险，特别是患癌风险。本综述重点关注了研究膳食补充剂使用与癌症发病风险及相关死亡率之间关联的文献。已有报道指出多种维生素、矿物质及其他膳食补充剂存在此类关联。尽管其中部分研究存在自身缺陷并受到批评，但它们必须引起人们对膳食补充剂长期不良反应的进一步研究关注，并建议消费者和医疗保健提供者审慎考虑膳食补充剂的广泛使用。
Supplement Use and Increased Risks of Cancer: Unveiling the Other Side of the Coin
肿瘤(癌症)患者之家