Pelvic exenteration represents a radical procedure aimed at achieving complete tumor resection with negative margins. Although it is the only therapeutic option for some cases of advanced tumors, it is associated with several perioperative complications. We believe that careful patient selection is related to better oncologic outcomes and lower complication rates. The objectives of this review are to identify the most current indications for this intervention, suggest criteria for case selection, evaluate recommendations for perioperative care, and review oncologic outcomes and potential associated complications. To this end, an analysis of English language articles in PubMed was performed, searching for topics such as the indication for pelvic exenteration for recurrent gynecologic neoplasms selection of oncologic cases, the impact of tumor size and extent on oncologic outcomes, preoperative and postoperative surgical management, surgical complications, and outcomes of overall survival and recurrence-free survival.
盆腔廓清术是一种旨在实现肿瘤完全切除且切缘阴性的根治性手术。尽管对于某些晚期肿瘤病例而言,这是唯一的治疗选择,但该手术伴随多种围手术期并发症。我们认为,细致的病例选择与更好的肿瘤学预后及更低的并发症发生率相关。本综述旨在明确该手术的最新适应症,提出病例选择标准,评估围手术期护理建议,并回顾肿瘤学预后及潜在相关并发症。为此,我们对PubMed数据库中的英文文献进行了分析,检索内容包括:复发性妇科肿瘤的盆腔廓清术适应症、肿瘤病例的选择标准、肿瘤大小及范围对肿瘤学预后的影响、术前与术后外科管理、手术并发症,以及总生存期和无复发生存期的预后情况。
The Role of Pelvic Exenteration in Cervical Cancer: A Review of the Literature