The study cohort consisted of 83 patients with a mean age of 49.55 (SD 13.72) with a female preponderance (60 patients). Here, 32.14% of patients had primary LTS; the remaining were metastases. Clinical presentation included nonspecific back pain (57.83%), weakness (21.69%) and radicular pain (18.07%). History of uterine neoplasia was found in 33.73% of patients. LTS preferentially affected the thoracic spine (51.81%), followed by the lumbar (21.67%) spine. MRI alone was the most common imaging modality (33.33%); in other cases, it was used with CT (22.92%) or X-ray (16.67%); 19.23% of patients had Resection/Fixation, 15.38% had Total en bloc spondylectomy, and 10.26% had Corpectomy. A minority of patients had laminectomy and decompression. Among those with resection, 45.83% had a gross total resection, 29.17% had a subtotal resection, and 16.67% had a near total resection. Immunohistochemistry demonstrated positivity for actin (43.37%), desmin (31.33%), and Ki67 (25.30). At a follow-up of 19.3 months, 61.97% of patients were alive; 26.25% of 80 patients received no additional treatment, 23.75% received combination radiotherapy and chemotherapy, only chemotherapy was given to 20%, and radiotherapy was given to 17.5%. Few (2.5%) had further resection. For an average of 12.50 months, 42.31% had no symptoms, while others had residual (19.23%), other metastasis (15.38%), and pain (7.69%). On follow-up of 29 patients, most (68.97%) had resolved symptoms; 61.97% of the 71 patients followed were alive.
本研究队列共纳入83例患者，平均年龄49.55岁（标准差13.72），女性占优势（60例）。其中32.14%为原发性腰椎肿瘤综合征（LTS），其余为转移性病变。临床表现包括非特异性背痛（57.83%）、肌力减弱（21.69%）和神经根性疼痛（18.07%）。33.73%的患者有子宫肿瘤病史。LTS好发于胸椎（51.81%），其次为腰椎（21.67%）。单纯MRI是最常见的影像学检查方式（33.33%）；其他病例中，MRI联合CT（22.92%）或X线（16.67%）使用。19.23%的患者接受切除术/固定术，15.38%接受全椎体整块切除术，10.26%接受椎体切除术。少数患者接受椎板切除减压术。在切除手术患者中，45.83%实现大体全切除，29.17%为次全切除，16.67%为近全切除。免疫组化显示肌动蛋白阳性率43.37%、结蛋白31.33%、Ki67指数25.30%。平均随访19.3个月后，61.97%患者存活；80例患者中26.25%未接受额外治疗，23.75%接受放化疗联合治疗，单纯化疗20%，单纯放疗17.5%，仅2.5%接受再次切除。在平均12.50个月随访期内，42.31%患者无症状，其余存在残余症状（19.23%）、其他部位转移（15.38%）或疼痛（7.69%）。对29例患者的随访显示，68.97%症状缓解；71例随访患者中61.97%存活。
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