Lung cancer remains a leading cause of death in the United States and globally, despite progress in treatment and screening efforts. While mortality rates have decreased in recent years, long-term survival of patients with lung cancer continues to be a challenge. Notably, African American (AA) men experience significant disparities in lung cancer compared to European Americans (EA) in terms of incidence, treatment, and survival. Previous studies have explored factors such as smoking patterns and complex social determinants, including socioeconomic status, personal beliefs, and systemic racism, indicating their role in these disparities. In addition to social factors, emerging evidence points to variations in tumor biology, immunity, and comorbid conditions contributing to racial disparities in this disease. This review emphasizes differences in smoking patterns, screening, and early detection and the intricate interplay of social, biological, and environmental conditions that make African Americans more susceptible to developing lung cancer and experiencing poorer outcomes.
肺癌在美国乃至全球范围内仍是主要的致死原因，尽管在治疗和筛查方面已取得进展。近年来死亡率虽有所下降，但肺癌患者的长期生存仍面临挑战。值得注意的是，非裔美国男性在肺癌发病率、治疗及生存率方面与欧裔美国人存在显著差异。既往研究已探讨了吸烟模式及复杂的社会决定因素（包括社会经济地位、个人信念和系统性种族主义）对差异形成的影响。除社会因素外，新近证据表明肿瘤生物学特征、免疫状态及共病情况的差异也导致了该疾病的种族差异性。本综述重点阐述吸烟模式、筛查与早期检测的差异，以及社会、生物和环境因素间复杂的相互作用如何使非裔美国人更易罹患肺癌且预后更差。
肿瘤(癌症)患者之家