Purpose: The aim of this study is to describe our initial experience using magnetic seeds (Magseed®) to guide breast-conserving surgery in non-palpable breast lesions and compare the use of magnetic seed with wires to guide breast-conserving surgery in terms of clinical and pathological characteristics. Methods: We performed a retrospective study including all breast-conserving surgeries for non-palpable breast lesions under 16 mm from June 2018 to May 2021. We compared breast-conserving surgeries guided with magnetic seeds (Magseed®) to those guided with wires, analyzing tumor and patient characteristics, surgical time, and pathological results of the surgical specimens. Results: Data from 225 cases were collected, including 149 cases guided by magnetic seeds and 76 cases guided by wires. The breast lesion was localized in every case. Both cohorts were similar regarding clinical and pathological characteristics. We found significant statistical differences (p< 0.02) in terms of the median volume (cm3) of the excised specimen, which was lower (29.3%) in the magnetic seed group compared with the wire group (32.5 [20.5–60.0]/46.0 [20.3–118.7]). We did not find significant differences regarding surgical time (min) or the affected or close margins. Conclusion: In our experience, the use of magnetic seed (Magseed®) is a feasible option to guide breast-conserving surgery of non-palpable lesions and enabled us to resect less breast tissue.
目的：本研究旨在描述我们使用磁性种子（Magseed®）引导非触及性乳腺病灶保乳手术的初步经验，并从临床与病理学特征角度比较磁性种子与导丝引导保乳手术的效果。方法：我们开展了一项回顾性研究，纳入2018年6月至2021年5月期间所有针对16毫米以下非触及性乳腺病灶的保乳手术。通过对比磁性种子（Magseed®）与导丝引导的手术病例，分析肿瘤及患者特征、手术时长以及手术标本的病理学结果。结果：共收集225例病例数据，其中磁性种子引导149例，导丝引导76例。所有病例均成功实现乳腺病灶定位。两组病例在临床与病理特征方面具有相似性。研究发现切除标本中位体积（立方厘米）存在显著统计学差异（p<0.02），磁性种子组切除体积较导丝组减少29.3%（32.5[20.5–60.0]/46.0[20.3–118.7]）。在手术时长（分钟）及切缘阳性或切缘过近方面未发现显著差异。结论：根据我们的经验，使用磁性种子（Magseed®）引导非触及性病灶保乳手术具有可行性，且能够实现更少量的乳腺组织切除。
Breast-Conserving Surgery Guided with Magnetic Seeds vs. Wires: A Single-Institution Experience
肿瘤(癌症)患者之家