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文章:

焦虑与抑郁作为甲状腺乳头状癌患者早期接受手术治疗时间的潜在预测因素

Anxiety and Depression as Potential Predictors for Shorter Time to Undergo Initial Surgical Treatment for Papillary Thyroid Cancer

原文发布日期:26 January 2024

DOI: 10.3390/cancers16030545

类型: Article

开放获取: 是

 

英文摘要:

(1) Background: A pre-existing psychiatric condition may impact decision making by patients and/or physicians following a thyroid cancer diagnosis, such as potentially electing surgery over active surveillance, thus shortening the time to cancer removal. This is the first study to investigate the association between pre-existing anxiety and/or depression and time to receive surgical treatment for thyroid cancer. (2) Methods: Retrospective data were collected from 652 surgical thyroid cancer patients at our institution from 2018 to 2020. We investigated the time between thyroid cancer diagnosis and surgery, comparing patients with pre-existing anxiety and/or depression to those without. (3) Results: Patients with anxiety, depression, and both anxiety and depression had a significantly shorter time between diagnosis and surgery (51.6, 57, and 57.4 days, respectively) compared to patients without (111.9 days) (p= 0.002,p= 0.004,p= 0.003, respectively). (4) Conclusions: Although little is known about the impact of pre-existing psychiatric conditions in the decision-making process for thyroid cancer surgery, this present study showed that anxiety and/or depression may lead to more immediate surgical interventions. Thus, psychiatric history may be an important factor for physicians to consider when counseling patients with thyroid cancer.

 

摘要翻译: 

(1) 背景:既存精神疾病可能影响甲状腺癌确诊后患者和/或医生的决策过程,例如可能促使患者选择手术而非主动监测,从而缩短癌症切除前的等待时间。本研究首次探讨既存焦虑和/或抑郁与甲状腺癌手术等待时间的关联性。(2) 方法:回顾性收集本机构2018年至2020年652例甲状腺癌手术患者资料,比较患有既存焦虑和/或抑郁的患者与无精神疾病患者在确诊至手术间隔时间的差异。(3) 结果:焦虑症患者、抑郁症患者及焦虑抑郁共病患者从确诊到手术的间隔时间(分别为51.6天、57天和57.4天)显著短于无精神疾病患者(111.9天)(p值分别为0.002、0.004、0.003)。(4) 结论:尽管目前关于既存精神疾病对甲状腺癌手术决策过程的影响认知有限,但本研究表明焦虑和/或抑郁可能导致更积极的手术干预。因此,精神病史应成为临床医生为甲状腺癌患者提供诊疗建议时需考量的重要因素。

 

原文链接:

Anxiety and Depression as Potential Predictors for Shorter Time to Undergo Initial Surgical Treatment for Papillary Thyroid Cancer

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