Thymectomy is the gold standard in the treatment of thymic neoplasm and plays a key role in the therapeutic path of myasthenia gravis. For years, sternotomy has been the traditional approach for removing anterior mediastinal lesions, although the robotic thymectomy is now widely performed. The literature is still lacking in papers comparing the two approaches and evaluating long-term oncological and neurological outcomes. This study aims to analyze the postoperative results of open and robotic thymectomy for thymic neoplasms in myasthenic patients. Surgical, oncological and neurological data of myasthenic patients affected by thymic neoplasms and surgically treated with extended thymectomy, both with the open and the robotic approach, in six Italian Thoracic Centers between 2011 and 2021 were evaluated. A total of 213 patients were enrolled in the study: 110 (51.6%) were treated with the open approach, and 103 (48.4%) were treated with robotic surgery. The open surgery, compared with the robotic, presented a shorter operating time (p< 0.001), a higher number of postoperative complications (p= 0.038) and longer postoperative hospitalization (p= 0.006). No other differences were observed in terms of surgical, oncological or neurological outcomes. The robotic approach can be considered safe and feasible, comparable to the open technique, in terms of surgical, oncological and neurological outcomes.
胸腺切除术是治疗胸腺肿瘤的金标准,并在重症肌无力的治疗路径中发挥关键作用。多年来,胸骨切开术一直是切除前纵隔病变的传统方法,尽管机器人胸腺切除术现已广泛应用。目前文献中仍缺乏比较这两种方法并评估长期肿瘤学和神经学结果的论文。本研究旨在分析重症肌无力患者胸腺肿瘤开放手术与机器人胸腺切除术的术后结果。本研究评估了2011年至2021年间,在意大利六家胸科中心接受扩大胸腺切除术(包括开放手术和机器人手术)治疗的重症肌无力合并胸腺肿瘤患者的手术、肿瘤学和神经学数据。共纳入213例患者:110例(51.6%)接受开放手术,103例(48.4%)接受机器人手术。与机器人手术相比,开放手术的手术时间更短(p<0.001),术后并发症更多(p=0.038),术后住院时间更长(p=0.006)。在手术、肿瘤学或神经学结果方面未观察到其他差异。就手术、肿瘤学和神经学结果而言,机器人手术可被视为安全可行,与开放技术相当。