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文章:

陷阱式胸廓切开术与蛤壳式胸廓切开术作为儿童神经母细胞瘤及其他胸部肿瘤的手术入路

Trap-Door Thoracotomy and Clamshell Thoracotomy as Surgical Approaches for Neuroblastoma and Other Thoracic Tumors in Children

原文发布日期:15 January 2024

DOI: 10.3390/cancers16020373

类型: Article

开放获取: 是

 

英文摘要:

Solid tumors of the cervicothoracic junction, the posterior mediastinum, or bilateral dorsal thoracic tumors represent a challenge in pediatric surgical oncology. The aim of this study was to evaluate trap-door thoracotomy and clamshell thoracotomy as surgical approaches. A single-center retrospective study of children with solid tumors in these specific localizations was performed. From 2015 to 2023, 26 children (17 girls; 9 boys) were treated at a median age of 54 months (range 8–229). Tumor resection was performed for neuroblastoma (n= 11); metastatic disease (n= 7); malignant rhabdoid tumor (n= 4); Ewing sarcoma (n= 1); inflammatory myofibroblastic tumor (n= 1); rhabdomyosarcoma (n= 1); and neurofibroma (n= 1). The surgical goal of macroscopic complete excision was achieved in all of the 14 children who underwent trap-door thoracotomy and in 11 of the 12 children who underwent clamshell thoracotomy. There were no major complications. At a median follow-up of 8 months (range 0–60), the disease was under local control or in complete remission in 66.7% of the children. In conclusion, surgical resection of solid tumors of the cervicothoracic junction in children can be performed safely and successfully with trap-door thoracotomy and with clamshell thoracotomy for posterior mediastinal or bilateral dorsal thoracic tumors.

 

摘要翻译: 

颈胸交界处、后纵隔或双侧胸背部的实体肿瘤是小儿外科肿瘤学中的治疗难点。本研究旨在评估"活板门"式胸廓切开术与"蛤壳"式胸廓切开术作为手术入路的临床应用效果。我们对特定部位实体肿瘤患儿进行了单中心回顾性研究。2015年至2023年间,共26例患儿(17例女性,9例男性)接受治疗,中位年龄54个月(范围8-229个月)。肿瘤切除病理类型包括:神经母细胞瘤(11例)、转移性疾病(7例)、恶性横纹肌样瘤(4例)、尤文氏肉瘤(1例)、炎性肌纤维母细胞瘤(1例)、横纹肌肉瘤(1例)和神经纤维瘤(1例)。所有14例接受"活板门"式胸廓切开术的患儿及12例接受"蛤壳"式胸廓切开术患儿中的11例均实现了肉眼完全切除的手术目标。研究期间未发生重大并发症。中位随访8个月(范围0-60个月)后,66.7%的患儿疾病达到局部控制或完全缓解。结论表明,采用"活板门"式胸廓切开术可安全有效地切除儿童颈胸交界处实体肿瘤,而"蛤壳"式胸廓切开术适用于后纵隔或双侧胸背部肿瘤的外科切除。

 

原文链接:

Trap-Door Thoracotomy and Clamshell Thoracotomy as Surgical Approaches for Neuroblastoma and Other Thoracic Tumors in Children

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